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- BRDT abstract "Bromodomain testis-specific protein is a protein that in humans is encoded by the BRDT gene.BRDT is similar to the RING3 protein family. It possesses 2 bromodomain motifs and a PEST sequence (a cluster of proline, glutamic acid, serine, and threonine residues), characteristic of proteins that undergo rapid intracellular degradation. The bromodomain is found in proteins that regulate transcription. Two transcript variants encoding the same protein have been found for this gene.The use of three different mouse models (Brdt knock-out mice, mice expressing a non-functional Brdt and mice expressing a mutated Brdt lacking its first bromodomain) showed that Brdt drives a meiotic and post-meiotic gene expression program. It also controls the genome-wide post-meiotic genome reorganization that occurs after histone hyperacetylation in elongating spermatids".
- BRDT entrezgene "676".
- BRDT wikiPageID "16855309".
- BRDT wikiPageRevisionID "590809357".
- BRDT hasPhotoCollection BRDT.
- BRDT requireManualInspection "no".
- BRDT summaryText "BRDT is similar to the RING3 protein family. It possesses 2 bromodomain motifs and a PEST sequence , characteristic of proteins that undergo rapid intracellular degradation. The bromodomain is found in proteins that regulate transcription. Two transcript variants encoding the same protein have been found for this gene.".
- BRDT updateCitations "yes".
- BRDT updatePage "yes".
- BRDT updateProteinBox "yes".
- BRDT updateSummary "yes".
- BRDT subject Category:Genes_mutated_in_mice.
- BRDT type Abstraction100002137.
- BRDT type Arrangement107938773.
- BRDT type Gene105436752.
- BRDT type GenesMutatedInMice.
- BRDT type Group100031264.
- BRDT type Ordering108456993.
- BRDT type Sequence108459252.
- BRDT type Series108457976.
- BRDT type Biomolecule.
- BRDT type Protein.
- BRDT type BiologicalObject.
- BRDT comment "Bromodomain testis-specific protein is a protein that in humans is encoded by the BRDT gene.BRDT is similar to the RING3 protein family. It possesses 2 bromodomain motifs and a PEST sequence (a cluster of proline, glutamic acid, serine, and threonine residues), characteristic of proteins that undergo rapid intracellular degradation. The bromodomain is found in proteins that regulate transcription.".
- BRDT label "BRDT".
- BRDT sameAs m.0408j7f.
- BRDT sameAs Q4836344.
- BRDT sameAs Q4836344.
- BRDT sameAs BRDT.
- BRDT wasDerivedFrom BRDT?oldid=590809357.
- BRDT isPrimaryTopicOf BRDT.