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- POZ_domain abstract "The BTB/POZ domain is a common structural domain contained within some proteins.The BTB (for BR-C, ttk and bab) or POZ (for Pox virus and Zinc finger) domain is present near the N-terminus of a fraction of zinc finger proteins and in proteins that contain the Kelch motif and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule. BTB/POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.".
- POZ_domain symbol "BTB".
- POZ_domain thumbnail PDB_1buo_EBI.jpg?width=300.
- POZ_domain wikiPageID "26658547".
- POZ_domain wikiPageRevisionID "590817556".
- POZ_domain caption "Structure of the BTB domain from PLZF.".
- POZ_domain hasPhotoCollection POZ_domain.
- POZ_domain interpro "IPR013069".
- POZ_domain name "BTB/POZ domain".
- POZ_domain pdb ", , , , , ,".
- POZ_domain pfam "PF00651".
- POZ_domain prosite "PS50097".
- POZ_domain scop "1".
- POZ_domain symbol "BTB".
- POZ_domain subject Category:Protein_domains.
- POZ_domain type Abstraction100002137.
- POZ_domain type Attribute100024264.
- POZ_domain type Environment113934596.
- POZ_domain type ProteinDomains.
- POZ_domain type Situation113927383.
- POZ_domain type Sphere114514039.
- POZ_domain type State100024720.
- POZ_domain type Biomolecule.
- POZ_domain type Protein.
- POZ_domain type BiologicalObject.
- POZ_domain comment "The BTB/POZ domain is a common structural domain contained within some proteins.The BTB (for BR-C, ttk and bab) or POZ (for Pox virus and Zinc finger) domain is present near the N-terminus of a fraction of zinc finger proteins and in proteins that contain the Kelch motif and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation.".
- POZ_domain label "BTB/POZ domain".
- POZ_domain sameAs m.0bh7hz1.
- POZ_domain sameAs Q4836667.
- POZ_domain sameAs Q4836667.
- POZ_domain sameAs POZ_domain.
- POZ_domain wasDerivedFrom POZ_domain?oldid=590817556.
- POZ_domain depiction PDB_1buo_EBI.jpg.
- POZ_domain isPrimaryTopicOf POZ_domain.