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- Benzoctamine abstract "Benzoctamine is a drug that possesses sedative and anxiolytic properties. Marketed as Tacitin by Ciba-Geigy, it is different from most sedative drugs because in most clinical trials it does not produce respiratory depression, but actually stimulates the respiratory system. As a result, when compared to other sedative and anxiolytic drugs such as alprazolam, librium, clonazepam, etc. it is a safer form of tranquilizing. However, when co-administered with other drugs that cause respiratory depression, like morphine, it can cause increased respiratory depression.Medically, benzoctamine is used as a treatment for anxious outpatients to control aggression, enuresis, fear, and minor social maladjustment in children. While it is a relatively new anti-anxiety drug, it’s popularity is increasing as a result of it being able to have comparable anxiolytic and sedative effects to other medications without their potentially fatal respiratory depressive side effects. Its pharmalogical effects are most similar to diazepam, another anxiolytic, but unlike diazepam, benzoctamine has antagonistic effects on epinephrine, norepinephrine, and appears to reduce serotonin turnover. While little is understood about how it carries out its effects, studies point to reduced serotonin, epinephrine, and norepinephrine as partial causes of its pharmacologic and behavioral effects.Animal studies have shown sedative hypnotic drugs tend to show dependency in animals, but benzoctamine has been shown to not be addictive. Other animal studies also point to the drug as a possible mechanism by which to reduce blood pressure through the adrenergic system.Chemically benzoctamine belongs to the class of new compounds called dibenzobicyclo-octodienes. It consists of four rings in a three dimensional configuration.".
- Benzoctamine atcPrefix "N05".
- Benzoctamine atcSuffix "BD01".
- Benzoctamine bioavailability "100.0".
- Benzoctamine casNumber "17243-09-9".
- Benzoctamine fdaUniiCode "734MM7Y191".
- Benzoctamine iupacName "N-methyl-9,10-ethanoanthracene-9(10H)-methanamine".
- Benzoctamine pubchem "28425".
- Benzoctamine thumbnail Benzoctamine.svg?width=300.
- Benzoctamine wikiPageID "12718675".
- Benzoctamine wikiPageRevisionID "603981317".
- Benzoctamine atcPrefix "N05".
- Benzoctamine atcSuffix "BD01".
- Benzoctamine bioavailability "100".
- Benzoctamine c "18".
- Benzoctamine casNumber "17243".
- Benzoctamine chemspiderid "26444".
- Benzoctamine eliminationHalfLife "10800.0".
- Benzoctamine excretion Kidney.
- Benzoctamine h "19".
- Benzoctamine hasPhotoCollection Benzoctamine.
- Benzoctamine inchi "1".
- Benzoctamine inchikey "GNRXCIONJWKSEA-UHFFFAOYAC".
- Benzoctamine iupacName "N-methyl-9,10-ethanoanthracene-9-methanamine".
- Benzoctamine legalStatus "legal".
- Benzoctamine metabolism Liver.
- Benzoctamine molecularWeight "249.35".
- Benzoctamine n "1".
- Benzoctamine pubchem "28425".
- Benzoctamine routesOfAdministration "Intravenous, oral".
- Benzoctamine smiles "c1ccc3cC4c2ccccc2C3CNC".
- Benzoctamine stdinchi "1".
- Benzoctamine stdinchikey "GNRXCIONJWKSEA-UHFFFAOYSA-N".
- Benzoctamine tradename "Tacitin".
- Benzoctamine unii "734".
- Benzoctamine verifiedrevid "447821248".
- Benzoctamine subject Category:Anxiolytics.
- Benzoctamine subject Category:Sedatives.
- Benzoctamine type Agent114778436.
- Benzoctamine type Anxiolytics.
- Benzoctamine type CausalAgent100007347.
- Benzoctamine type Drug103247620.
- Benzoctamine type DrugOfAbuse103248958.
- Benzoctamine type Matter100020827.
- Benzoctamine type Medicine103740161.
- Benzoctamine type MinorTranquilizer103771443.
- Benzoctamine type PhysicalEntity100001930.
- Benzoctamine type PsychotropicAgent104017429.
- Benzoctamine type Sedative-hypnotic104166841.
- Benzoctamine type Sedative104166553.
- Benzoctamine type Sedatives.
- Benzoctamine type Substance100020090.
- Benzoctamine type Tranquilizer104470232.
- Benzoctamine type Drug.
- Benzoctamine type DrugProduct.
- Benzoctamine type FunctionalSubstance.
- Benzoctamine comment "Benzoctamine is a drug that possesses sedative and anxiolytic properties. Marketed as Tacitin by Ciba-Geigy, it is different from most sedative drugs because in most clinical trials it does not produce respiratory depression, but actually stimulates the respiratory system. As a result, when compared to other sedative and anxiolytic drugs such as alprazolam, librium, clonazepam, etc. it is a safer form of tranquilizing.".
- Benzoctamine label "Benzoctamine".
- Benzoctamine sameAs m.02x2185.
- Benzoctamine sameAs Q4890786.
- Benzoctamine sameAs Q4890786.
- Benzoctamine sameAs Benzoctamine.
- Benzoctamine wasDerivedFrom Benzoctamine?oldid=603981317.
- Benzoctamine depiction Benzoctamine.svg.
- Benzoctamine isPrimaryTopicOf Benzoctamine.