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- Beta_amyloid abstract "Amyloid-beta (Aβ or Abeta) denotes peptides of 36–43 amino acids that are crucially involved in Alzheimer's disease as the main component of the amyloid plaques found in the brains of Alzheimer patients. The peptides result from the amyloid precursor protein (APP), which is being cut by certain enzymes to yield Aβ. Aβ molecules can aggregate to form flexible soluble oligomers which may exist in several forms. It is now believed that certain misfolded oligomers (known as "seeds") can induce other Aβ molecules to also take the misfolded oligomeric form, leading to a chain reaction akin to a prion infection. The seeds or the resulting amyloid plaques are toxic to nerve cells. The other protein implicated in Alzheimer's disease, tau protein, also forms such prion-like misfolded oligomers, and there is some evidence that misfolded Aβ can induce tau to misfold.A recent study suggested that APP and its amyloid potential is of ancient origins, dating as far back as early deuterostomes.".
- Beta_amyloid arm "q".
- Beta_amyloid band "21.2".
- Beta_amyloid chromosome "21".
- Beta_amyloid entrezgene "351".
- Beta_amyloid hgncid "620".
- Beta_amyloid omim "104760".
- Beta_amyloid refseq "NM_000484".
- Beta_amyloid symbol "AD1".
- Beta_amyloid symbol "APP".
- Beta_amyloid thumbnail Abeta_2lfm.jpg?width=300.
- Beta_amyloid uniprot "P05067".
- Beta_amyloid wikiPageID "1958222".
- Beta_amyloid wikiPageRevisionID "603461257".
- Beta_amyloid altsymbols "AD1".
- Beta_amyloid arm "q".
- Beta_amyloid band "21.2".
- Beta_amyloid caption "A partially folded structure of amyloid-beta in an aqueous environment".
- Beta_amyloid caption "Processing of the amyloid precursor protein".
- Beta_amyloid chromosome "21".
- Beta_amyloid entrezgene "351".
- Beta_amyloid hasPhotoCollection Beta_amyloid.
- Beta_amyloid hgncid "620".
- Beta_amyloid interpro "IPR013803".
- Beta_amyloid name "Beta-amyloid peptide".
- Beta_amyloid name "amyloid-beta precursor protein".
- Beta_amyloid omim "104760".
- Beta_amyloid opmFamily "369".
- Beta_amyloid opmProtein "2".
- Beta_amyloid pfam "PF03494".
- Beta_amyloid refseq "NM_000484".
- Beta_amyloid scop "2".
- Beta_amyloid symbol Amyloid_precursor_protein.
- Beta_amyloid symbol "APP".
- Beta_amyloid tcdb "1".
- Beta_amyloid uniprot "P05067".
- Beta_amyloid width "300".
- Beta_amyloid subject Category:Alzheimer's_disease.
- Beta_amyloid subject Category:Amyloidosis.
- Beta_amyloid subject Category:Molecular_neuroscience.
- Beta_amyloid subject Category:Peptides.
- Beta_amyloid type Abstraction100002137.
- Beta_amyloid type Activator114723079.
- Beta_amyloid type Catalyst114723628.
- Beta_amyloid type Chemical114806838.
- Beta_amyloid type Compound114818238.
- Beta_amyloid type Enzyme114732946.
- Beta_amyloid type Enzymes.
- Beta_amyloid type IntegralMembraneProteins.
- Beta_amyloid type Macromolecule114944888.
- Beta_amyloid type Material114580897.
- Beta_amyloid type Matter100020827.
- Beta_amyloid type Molecule114682133.
- Beta_amyloid type OrganicCompound114727670.
- Beta_amyloid type Part113809207.
- Beta_amyloid type PhysicalEntity100001930.
- Beta_amyloid type Protein114728724.
- Beta_amyloid type Relation100031921.
- Beta_amyloid type Substance100019613.
- Beta_amyloid type Thing100002452.
- Beta_amyloid type Unit109465459.
- Beta_amyloid type Biomolecule.
- Beta_amyloid type Protein.
- Beta_amyloid type ProteinMolecule.
- Beta_amyloid type BiologicalObject.
- Beta_amyloid comment "Amyloid-beta (Aβ or Abeta) denotes peptides of 36–43 amino acids that are crucially involved in Alzheimer's disease as the main component of the amyloid plaques found in the brains of Alzheimer patients. The peptides result from the amyloid precursor protein (APP), which is being cut by certain enzymes to yield Aβ. Aβ molecules can aggregate to form flexible soluble oligomers which may exist in several forms.".
- Beta_amyloid label "Beta amyloid".
- Beta_amyloid label "Beta-Amyloid".
- Beta_amyloid label "Beta-amiloide".
- Beta_amyloid label "Betamiloide".
- Beta_amyloid label "Bêta-amyloïde".
- Beta_amyloid label "أميلويد بيتا".
- Beta_amyloid sameAs Amyloid_beta.
- Beta_amyloid sameAs Beta-Amyloid.
- Beta_amyloid sameAs Beta-amiloide.
- Beta_amyloid sameAs Bêta-amyloïde.
- Beta_amyloid sameAs Betamiloide.
- Beta_amyloid sameAs m.068zh0.
- Beta_amyloid sameAs Q417667.
- Beta_amyloid sameAs Q417667.
- Beta_amyloid sameAs Beta_amyloid.
- Beta_amyloid wasDerivedFrom Beta_amyloid?oldid=603461257.
- Beta_amyloid depiction Abeta_2lfm.jpg.
- Beta_amyloid isPrimaryTopicOf Beta_amyloid.
- Beta_amyloid name "amyloid-beta (A4) precursor protein (peptidase nexin-II, Alzheimer disease)".