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- Biphenylindanone_A abstract "Biphenylindanone A (BINA, LS-193,571) is a research agent which acts as a potent and selective positive allosteric modulator for the group II metabotropic glutamate receptor subtype mGluR2. In animal studies it showed anxiolytic and antipsychotic effects, and blocked the effects produced by the hallucinogenic drug DOB. BINA and other selective mGluR2 positive modulators have therefore been suggested as a novel class of drugs for the treatment of schizophrenia which may have superior properties to traditional antipsychotic drugs.BINA decreases cocaine self-administration in rats, with no effect on food self-administration, and is in regard to this discrimination superior to the mGluR2/3 agonist LY-379,268".
- Biphenylindanone_A atcPrefix "none".
- Biphenylindanone_A iupacName "3’-(((2-cyclopentyl-6,7-dimethyl-1-oxo-2,3-dihydro- 1H-inden-5-yl)oxy)methyl)biphenyl-4-carboxylic acid".
- Biphenylindanone_A pubchem "9868580".
- Biphenylindanone_A thumbnail Biphenylindanone2DACS.svg?width=300.
- Biphenylindanone_A wikiPageID "19393048".
- Biphenylindanone_A wikiPageRevisionID "600770959".
- Biphenylindanone_A atcPrefix "none".
- Biphenylindanone_A c "30".
- Biphenylindanone_A chembl "593013".
- Biphenylindanone_A chemspiderid "8044271".
- Biphenylindanone_A h "30".
- Biphenylindanone_A hasPhotoCollection Biphenylindanone_A.
- Biphenylindanone_A inchi "1".
- Biphenylindanone_A inchikey "KMKBEESNZAPKMP-UHFFFAOYAW".
- Biphenylindanone_A iupacName "3".
- Biphenylindanone_A molecularWeight "454.556".
- Biphenylindanone_A o "4".
- Biphenylindanone_A pubchem "9868580".
- Biphenylindanone_A smiles "c3ccccc3-ccc4COcccCC2C5CCCC5".
- Biphenylindanone_A stdinchi "1".
- Biphenylindanone_A stdinchikey "KMKBEESNZAPKMP-UHFFFAOYSA-N".
- Biphenylindanone_A verifiedrevid "477372869".
- Biphenylindanone_A width "300".
- Biphenylindanone_A subject Category:Antipsychotics.
- Biphenylindanone_A subject Category:Anxiolytics.
- Biphenylindanone_A type Agent114778436.
- Biphenylindanone_A type Antipsychotics.
- Biphenylindanone_A type Anxiolytics.
- Biphenylindanone_A type CausalAgent100007347.
- Biphenylindanone_A type Drug103247620.
- Biphenylindanone_A type DrugOfAbuse103248958.
- Biphenylindanone_A type MajorTranquilizer103713736.
- Biphenylindanone_A type Matter100020827.
- Biphenylindanone_A type Medicine103740161.
- Biphenylindanone_A type MinorTranquilizer103771443.
- Biphenylindanone_A type PhysicalEntity100001930.
- Biphenylindanone_A type PsychotropicAgent104017429.
- Biphenylindanone_A type Sedative-hypnotic104166841.
- Biphenylindanone_A type Sedative104166553.
- Biphenylindanone_A type Substance100020090.
- Biphenylindanone_A type Tranquilizer104470232.
- Biphenylindanone_A type Drug.
- Biphenylindanone_A type DrugProduct.
- Biphenylindanone_A type FunctionalSubstance.
- Biphenylindanone_A comment "Biphenylindanone A (BINA, LS-193,571) is a research agent which acts as a potent and selective positive allosteric modulator for the group II metabotropic glutamate receptor subtype mGluR2. In animal studies it showed anxiolytic and antipsychotic effects, and blocked the effects produced by the hallucinogenic drug DOB.".
- Biphenylindanone_A label "Biphenylindanone A".
- Biphenylindanone_A sameAs m.04n1hc8.
- Biphenylindanone_A sameAs Q4915436.
- Biphenylindanone_A sameAs Q4915436.
- Biphenylindanone_A sameAs Biphenylindanone_A.
- Biphenylindanone_A wasDerivedFrom Biphenylindanone_A?oldid=600770959.
- Biphenylindanone_A depiction Biphenylindanone2DACS.svg.
- Biphenylindanone_A isPrimaryTopicOf Biphenylindanone_A.