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- Buserelin abstract "Buserelin is a Gonadotropin-releasing hormone agonist (GnRH agonist). The drug's effects are dependent on the frequency and time course of administration. GnRH is released in a pulsatile fashion in the postpubertal adult. Initial interaction of any GnRH agonist, such as buserelin, with the GnRH receptor induces release of FSH and LH by gonadotrophes. Long-term exposure to constant levels of buserelin, rather than endogenous pulses, leads to downregulation of the GnRH receptors and subsequent suppression of the pituitary release of LH and FSH.Like other GnRH agonists, buserelin may be used in the treatment of hormone-responsive cancers such as prostate cancer or breast cancer, estrogen-dependent conditions (such as endometriosis or uterine fibroids), and in assisted reproduction.It is normally delivered via a nasal spray, but is also available as an injection.Buserelin acetate is marketed by Sanofi-Aventis under the brand name Suprefact and a generic form of Buserelin is now produced by CinnaGen under the brand name CinnaFact.Buserelin is also marketed under the brand name Metrelef. Metrelef is approved to treat patients with endometriosis by suppression of ovarian hormone production. In ovulation induction Metrelef is used as a pituitary blockade as an adjunct to gonadotrophin administration.".
- Buserelin atcPrefix "L02".
- Buserelin atcSuffix "AE01".
- Buserelin casNumber "57982-77-1".
- Buserelin drugbank "DB06719".
- Buserelin fdaUniiCode "PXW8U3YXDV".
- Buserelin pubchem "50225".
- Buserelin thumbnail Buserelin.svg?width=300.
- Buserelin wikiPageID "2102388".
- Buserelin wikiPageRevisionID "585829044".
- Buserelin atcPrefix "L02".
- Buserelin atcSuffix "AE01".
- Buserelin c "62".
- Buserelin casNumber "57982".
- Buserelin chembl "1909304".
- Buserelin chemspiderid "45545".
- Buserelin drugbank "DB06719".
- Buserelin eliminationHalfLife "4800.0".
- Buserelin excretion Kidney.
- Buserelin h "90".
- Buserelin hasPhotoCollection Buserelin.
- Buserelin inchi "1".
- Buserelin inchikey "CUWODFFVMXJOKD-UVLQAERKBG".
- Buserelin legalStatus "℞-only".
- Buserelin molecularWeight "1299.48".
- Buserelin n "16".
- Buserelin o "15".
- Buserelin pregnancyCategory "X".
- Buserelin pubchem "50225".
- Buserelin routesOfAdministration "implant, intranasal".
- Buserelin stdinchi "1".
- Buserelin stdinchikey "CUWODFFVMXJOKD-UVLQAERKSA-N".
- Buserelin synonyms "D-Ser6EA10LHRH".
- Buserelin tradename "Etilamide".
- Buserelin unii "PXW8U3YXDV".
- Buserelin verifiedfields "changed".
- Buserelin verifiedrevid "477165149".
- Buserelin subject Category:GnRH_agonists.
- Buserelin type Drug.
- Buserelin type DrugProduct.
- Buserelin type FunctionalSubstance.
- Buserelin comment "Buserelin is a Gonadotropin-releasing hormone agonist (GnRH agonist). The drug's effects are dependent on the frequency and time course of administration. GnRH is released in a pulsatile fashion in the postpubertal adult. Initial interaction of any GnRH agonist, such as buserelin, with the GnRH receptor induces release of FSH and LH by gonadotrophes.".
- Buserelin label "Buserelin".
- Buserelin label "Buserelin".
- Buserelin label "Buserelina".
- Buserelin label "Buserelina".
- Buserelin sameAs Buserelin.
- Buserelin sameAs Buserelina.
- Buserelin sameAs Buserelina.
- Buserelin sameAs m.06m8lm.
- Buserelin sameAs Q414745.
- Buserelin sameAs Q414745.
- Buserelin wasDerivedFrom Buserelin?oldid=585829044.
- Buserelin depiction Buserelin.svg.
- Buserelin isPrimaryTopicOf Buserelin.