Matches in DBpedia 2014 for { <http://dbpedia.org/resource/CHAP_domain> ?p ?o. }
Showing items 1 to 33 of
33
with 100 items per page.
- CHAP_domain abstract "In molecular biology, the CHAP domain is a region between 110 and 140 amino acids that is found in proteins from bacteria, bacteriophages, archaea and eukaryotes of the Trypanosomidae family. The domain is named after the acronym cysteine, histidine-dependent amidohydrolases/peptidases. Many of these proteins are uncharacterised, but it has been proposed that they may function mainly in peptidoglycan hydrolysis. The CHAP domain is found in a wide range of protein architectures; it is commonly associated with bacterial type SH3 domains and with several families of amidase domains. It has been suggested that CHAP domain containing proteins utilise a catalytic cysteine residue in a nucleophilic-attack mechanism.The CHAP domain contains two invariant residues, a cysteine and a histidine. These residues form part of the putative active site of CHAP domain containing proteins. Secondary structure predictions show that the CHAP domain belongs to the alpha + beta structural class, with the N-terminal half largely containing predicted alpha helices and the C-terminal half principally composed of predicted beta strands.Some proteins known to contain a CHAP domain are listed below: Bacterial and trypanosomal glutathionylspermidine amidases. A variety of bacterial autolysins. A Nocardia aerocolonigenes putative esterase. Streptococcus pneumoniae choline-binding protein D. Methanosarcina mazei protein MM2478, a putative chloride channel. Several phage-encoded peptidoglycan hydrolases. Cysteine peptidases belonging to MEROPS peptidase family C51 (D-alanyl-glycyl endopeptidase, clan CA).↑ 1.0 1.1 ↑ 2.0 2.1".
- CHAP_domain symbol "CHAP".
- CHAP_domain thumbnail PDB_2ioa_EBI.jpg?width=300.
- CHAP_domain wikiPageID "31685884".
- CHAP_domain wikiPageRevisionID "590891270".
- CHAP_domain caption "E. coli Bifunctional glutathionylspermidine synthetase/amidase In complex with Mg2+ and ADP and phosphinate inhibitor.".
- CHAP_domain hasPhotoCollection CHAP_domain.
- CHAP_domain interpro "IPR007921".
- CHAP_domain merops "51.0".
- CHAP_domain name "CHAP".
- CHAP_domain pfam "PF05257".
- CHAP_domain pfamClan "CL0125".
- CHAP_domain symbol "CHAP".
- CHAP_domain subject Category:Protein_domains.
- CHAP_domain type Abstraction100002137.
- CHAP_domain type Attribute100024264.
- CHAP_domain type Environment113934596.
- CHAP_domain type ProteinDomains.
- CHAP_domain type Situation113927383.
- CHAP_domain type Sphere114514039.
- CHAP_domain type State100024720.
- CHAP_domain type Biomolecule.
- CHAP_domain type Protein.
- CHAP_domain type BiologicalObject.
- CHAP_domain comment "In molecular biology, the CHAP domain is a region between 110 and 140 amino acids that is found in proteins from bacteria, bacteriophages, archaea and eukaryotes of the Trypanosomidae family. The domain is named after the acronym cysteine, histidine-dependent amidohydrolases/peptidases. Many of these proteins are uncharacterised, but it has been proposed that they may function mainly in peptidoglycan hydrolysis.".
- CHAP_domain label "CHAP domain".
- CHAP_domain sameAs m.0gmgmv_.
- CHAP_domain sameAs Q5011040.
- CHAP_domain sameAs Q5011040.
- CHAP_domain sameAs CHAP_domain.
- CHAP_domain wasDerivedFrom CHAP_domain?oldid=590891270.
- CHAP_domain depiction PDB_2ioa_EBI.jpg.
- CHAP_domain isPrimaryTopicOf CHAP_domain.