Matches in DBpedia 2014 for { <http://dbpedia.org/resource/CMA1> ?p ?o. }
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- CMA1 abstract "Chymase is an enzyme that in humans is encoded by the CMA1 gene.This gene product is a chymotryptic serine proteinase that belongs to the peptidase family S1. It is expressed in mast cells and thought to function in the degradation of the extracellular matrix, the regulation of submucosal gland secretion, and the generation of vasoactive peptides. In the heart and blood vessels, this protein, rather than angiotensin converting enzyme, is largely responsible for converting angiotensin I to the vasoactive peptide angiotensin II. Angiotensin II has been implicated in blood pressure control and in the pathogenesis of hypertension, cardiac hypertrophy, and heart failure. Thus, this gene product is a target for cardiovascular disease therapies. This gene maps to 14q11.2 in a cluster of genes encoding other proteases.".
- CMA1 entrezgene "1215".
- CMA1 wikiPageID "14143626".
- CMA1 wikiPageRevisionID "601781534".
- CMA1 hasPhotoCollection CMA1.
- CMA1 requireManualInspection "no".
- CMA1 summaryText "This gene product is a chymotryptic serine proteinase that belongs to the peptidase family S1. It is expressed in mast cells and thought to function in the degradation of the extracellular matrix, the regulation of submucosal gland secretion, and the generation of vasoactive peptides. In the heart and blood vessels, this protein, rather than angiotensin converting enzyme, is largely responsible for converting angiotensin I to the vasoactive peptide angiotensin II. Angiotensin II has been implicated in blood pressure control and in the pathogenesis of hypertension, cardiac hypertrophy, and heart failure. Thus, this gene product is a target for cardiovascular disease therapies. This gene maps to 14q11.2 in a cluster of genes encoding other proteases.".
- CMA1 updateCitations "yes".
- CMA1 updatePage "yes".
- CMA1 updateProteinBox "yes".
- CMA1 updateSummary "yes".
- CMA1 type Biomolecule.
- CMA1 type Protein.
- CMA1 type BiologicalObject.
- CMA1 comment "Chymase is an enzyme that in humans is encoded by the CMA1 gene.This gene product is a chymotryptic serine proteinase that belongs to the peptidase family S1. It is expressed in mast cells and thought to function in the degradation of the extracellular matrix, the regulation of submucosal gland secretion, and the generation of vasoactive peptides.".
- CMA1 label "CMA1".
- CMA1 sameAs CMA1.
- CMA1 sameAs m.03cvygn.
- CMA1 sameAs Q5012835.
- CMA1 sameAs Q5012835.
- CMA1 sameAs 1615.
- CMA1 wasDerivedFrom CMA1?oldid=601781534.
- CMA1 isPrimaryTopicOf CMA1.