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- CP_55,940 abstract "CP 55,940 is a cannabinoid which mimics the effects of naturally occurring THC (one of the psychoactive compounds found in cannabis). CP 55,940 was created by Pfizer in 1974 but was never marketed. It is currently used to study the endocannabinoid system. Some effects that have been noted are a greatly decreased rates of lever pressing in exposed mice,[citation needed] and a greater reaction to opiates in exposed mice.[citation needed]A study found that CP 55,940 can upregulate 5-HT2A receptors in mice.CP 55,940 is 45 times more potent than Δ9-THC, and fully antagonized by rimonabant (SR141716A).CP 55,940 is considered a full agonist at both CB1 and CB2 receptors and has Ki values of 0.58nM and 0.68nM respectively, but is an antagonist at GPR55, the putative "CB3" receptor.CP 55,940 showed protective effects on rat brain mitochondria upon paraquat exposure.It also showed neuroprotective effects by reducing intracellular calcium release and reducing hippocampal cell death in cultured neurons subjected to high levels of NMDA.CP 55,940 induced cell death in NG 108-15 Mouse neuroblastoma x Rat glioma hybrid brain cancer (genetically engineered mouse x rat brain cancer) cells.".
- CP_55,940 casNumber "83002-04-4".
- CP_55,940 iupacName "2-[(1R,2R,5R)-5-hydroxy-2-(3-hydroxypropyl) cyclohexyl]-5-(2-methyloctan-2-yl)phenol".
- CP_55,940 pubchem "3086156".
- CP_55,940 thumbnail CP_55,940-2D-skeletal.svg?width=300.
- CP_55,940 wikiPageID "863748".
- CP_55,940 wikiPageRevisionID "604197477".
- CP_55,940 c "24".
- CP_55,940 casNumber "83002".
- CP_55,940 chembl "559612".
- CP_55,940 h "40".
- CP_55,940 hasPhotoCollection CP_55,940.
- CP_55,940 iupacName "2".
- CP_55,940 molecularWeight "376.573".
- CP_55,940 o "3".
- CP_55,940 pubchem "3086156".
- CP_55,940 smiles "O[C@H]1C[C@@H][C@H]CC1".
- CP_55,940 width "200".
- CP_55,940 subject Category:Alcohols.
- CP_55,940 subject Category:CB1_receptor_agonist.
- CP_55,940 subject Category:CB2_receptor_agonist.
- CP_55,940 subject Category:Cannabinoids.
- CP_55,940 subject Category:Designer_drugs.
- CP_55,940 subject Category:Pfizer.
- CP_55,940 subject Category:Phenols.
- CP_55,940 type Drug.
- CP_55,940 type DrugProduct.
- CP_55,940 type FunctionalSubstance.
- CP_55,940 comment "CP 55,940 is a cannabinoid which mimics the effects of naturally occurring THC (one of the psychoactive compounds found in cannabis). CP 55,940 was created by Pfizer in 1974 but was never marketed. It is currently used to study the endocannabinoid system.".
- CP_55,940 label "CP 55,940".
- CP_55,940 label "CP 55,940".
- CP_55,940 sameAs CP_55,940.
- CP_55,940 sameAs m.03jj7r.
- CP_55,940 sameAs Q5013768.
- CP_55,940 sameAs Q5013768.
- CP_55,940 wasDerivedFrom CP_55,940?oldid=604197477.
- CP_55,940 depiction CP_55,940-2D-skeletal.svg.
- CP_55,940 isPrimaryTopicOf CP_55,940.