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- CREB abstract "CREB (cAMP response element-binding protein) is a cellular transcription factor. It binds to certain DNA sequences called cAMP response elements (CRE), thereby increasing or decreasing the transcription of the downstream genes.CREB was first described in 1987 as a cAMP-responsive transcription factor regulating the somatostatin gene.Genes whose transcription is regulated by CREB include: c-fos, the neurotrophin BDNF (brain-derived neurotrophic factor), tyrosine hydroxylase, and many neuropeptides (such as somatostatin, enkephalin, VGF, and corticotropin-releasing hormone).CREB is closely related in structure and function to CREM (cAMP response element modulator) and ATF-1 (activating transcription factor-1) proteins. CREB proteins are expressed in many animals, including humans.CREB has a well-documented role in neuronal plasticity and long-term memory formation in the brain. CREB has been shown to be integral in the formation of spatial memory. In recent experiments it has been demonstrated that CREB may possess therapeutic potential for patients that have Alzheimer's disease.".
- CREB thumbnail CREB.png?width=300.
- CREB wikiPageExternalLink neuroscience.html.
- CREB wikiPageExternalLink dcreba1.htm.
- CREB wikiPageExternalLink dcreb2.htm.
- CREB wikiPageExternalLink what-turns-creb-on.
- CREB wikiPageID "743466".
- CREB wikiPageRevisionID "606489504".
- CREB hasPhotoCollection CREB.
- CREB subject Category:Transcription_factors.
- CREB type Abstraction100002137.
- CREB type Beginning107290905.
- CREB type Cause107326557.
- CREB type Event100029378.
- CREB type Factor107327805.
- CREB type Happening107283608.
- CREB type Origin107323922.
- CREB type PsychologicalFeature100023100.
- CREB type TranscriptionFactors.
- CREB type YagoPermanentlyLocatedEntity.
- CREB comment "CREB (cAMP response element-binding protein) is a cellular transcription factor.".
- CREB label "CREB (protéine)".
- CREB label "CREB".
- CREB label "CREB".
- CREB label "CREB".
- CREB label "CREB".
- CREB sameAs CREB.
- CREB sameAs CREB_(protéine).
- CREB sameAs CREB.
- CREB sameAs m.037m9m.
- CREB sameAs Q2931970.
- CREB sameAs Q2931970.
- CREB sameAs CREB.
- CREB wasDerivedFrom CREB?oldid=606489504.
- CREB depiction CREB.png.
- CREB isPrimaryTopicOf CREB.