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- CVNH_domain abstract "In molecular biology, the CVNH domain (CyanoVirin-N Homology domain) is a conserved protein domain. It is found in the sugar-binding antiviral protein cyanovirin-N (CVN) as well as proteins from filamentous ascomycetes and in the fern Ceratopteris richardii.Cyanovirin-N (CV-N) is an 11-kDa protein from the cyanobacterium Nostoc ellipsosporum that displays virucidal activity against several viruses, including human immunodeficiency virus (AIDS). The virucidal activity of CV-N is mediated through specific high-affinity interactions with the viral surface envelope glycoproteins gp120 and gp41, as well as to high-mannose oligosaccharides found on the HIV envelope. In addition, CV-N is active against rhinoviruses, human parainfluenza virus, respiratory syncytial virus, and enteric viruses. The virucidal activity of CV-N against influenza virus is directed towards viral haemagglutinin. CV-N has a complex fold composed of a duplication of a tandem repeat of two homologous motifs comprising three-stranded beta sheet and beta hairpins.".
- CVNH_domain symbol "CVNH".
- CVNH_domain thumbnail PDB_1iiy_EBI.jpg?width=300.
- CVNH_domain wikiPageID "32559204".
- CVNH_domain wikiPageRevisionID "593921793".
- CVNH_domain caption "solution nmr structure of complex of 1:2 cyanovirin-n:man-alpha1,2-man-alpha restrained regularized mean coordinates".
- CVNH_domain hasPhotoCollection CVNH_domain.
- CVNH_domain interpro "IPR011058".
- CVNH_domain name "CVNH".
- CVNH_domain pfam "PF08881".
- CVNH_domain symbol "CVNH".
- CVNH_domain subject Category:Protein_domains.
- CVNH_domain type Abstraction100002137.
- CVNH_domain type Attribute100024264.
- CVNH_domain type Environment113934596.
- CVNH_domain type ProteinDomains.
- CVNH_domain type Situation113927383.
- CVNH_domain type Sphere114514039.
- CVNH_domain type State100024720.
- CVNH_domain type Biomolecule.
- CVNH_domain type Protein.
- CVNH_domain type BiologicalObject.
- CVNH_domain comment "In molecular biology, the CVNH domain (CyanoVirin-N Homology domain) is a conserved protein domain. It is found in the sugar-binding antiviral protein cyanovirin-N (CVN) as well as proteins from filamentous ascomycetes and in the fern Ceratopteris richardii.Cyanovirin-N (CV-N) is an 11-kDa protein from the cyanobacterium Nostoc ellipsosporum that displays virucidal activity against several viruses, including human immunodeficiency virus (AIDS).".
- CVNH_domain label "CVNH domain".
- CVNH_domain sameAs m.0h1d677.
- CVNH_domain sameAs Q5014770.
- CVNH_domain sameAs Q5014770.
- CVNH_domain sameAs CVNH_domain.
- CVNH_domain wasDerivedFrom CVNH_domain?oldid=593921793.
- CVNH_domain depiction PDB_1iiy_EBI.jpg.
- CVNH_domain isPrimaryTopicOf CVNH_domain.