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- Cancer_stem_cell abstract "Cancer stem cells (CSCs) are cancer cells (found within tumors or hematological cancers) that possess characteristics associated with normal stem cells, specifically the ability to give rise to all cell types found in a particular cancer sample. CSCs are therefore tumorigenic (tumor-forming), perhaps in contrast to other non-tumorigenic cancer cells. CSCs may generate tumors through the stem cell processes of self-renewal and differentiation into multiple cell types. Such cells are proposed to persist in tumors as a distinct population and cause relapse and metastasis by giving rise to new tumors. Therefore, development of specific therapies targeted at CSCs holds hope for improvement of survival and quality of life of cancer patients, especially for sufferers of metastatic disease.Existing cancer treatments have mostly been developed based on animal models, where therapies able to promote tumor shrinkage were deemed effective. However, animals could not provide a complete model of human disease. In particular, in mice, whose life spans do not exceed two years, tumor relapse is exceptionally difficult to study.The efficacy of cancer treatments is, in the initial stages of testing, often measured by the ablation fraction of tumor mass (fractional kill). As CSCs would form a very small proportion of the tumor, this may not necessarily select for drugs that act specifically on the stem cells. The theory suggests that conventional chemotherapies kill differentiated or differentiating cells, which form the bulk of the tumor but are unable to generate new cells. A population of CSCs, which gave rise to it, could remain untouched and cause a relapse of the disease.".
- Cancer_stem_cell thumbnail Cancer_stem_cells_text_resized.svg?width=300.
- Cancer_stem_cell wikiPageExternalLink ?p=1772.
- Cancer_stem_cell wikiPageExternalLink cancerstemcellnews.blogspot.com.
- Cancer_stem_cell wikiPageExternalLink special-characteristics-of-cancer-cells.
- Cancer_stem_cell wikiPageExternalLink cancerstemcell.
- Cancer_stem_cell wikiPageExternalLink ATumorsLifeblood.aspx.
- Cancer_stem_cell wikiPageExternalLink stem_c.shtml.
- Cancer_stem_cell wikiPageExternalLink 18511937.
- Cancer_stem_cell wikiPageExternalLink ?id=14891.
- Cancer_stem_cell wikiPageExternalLink 33455.aspx.
- Cancer_stem_cell wikiPageExternalLink bob8.asp.
- Cancer_stem_cell wikiPageExternalLink CSCsci.htm.
- Cancer_stem_cell wikiPageID "2448941".
- Cancer_stem_cell wikiPageRevisionID "604773128".
- Cancer_stem_cell hasPhotoCollection Cancer_stem_cell.
- Cancer_stem_cell subject Category:Carcinogenesis.
- Cancer_stem_cell subject Category:Stem_cells.
- Cancer_stem_cell type Cell100006484.
- Cancer_stem_cell type LivingThing100004258.
- Cancer_stem_cell type Object100002684.
- Cancer_stem_cell type PhysicalEntity100001930.
- Cancer_stem_cell type SomaticCell105430628.
- Cancer_stem_cell type StemCell105607863.
- Cancer_stem_cell type StemCells.
- Cancer_stem_cell type Whole100003553.
- Cancer_stem_cell comment "Cancer stem cells (CSCs) are cancer cells (found within tumors or hematological cancers) that possess characteristics associated with normal stem cells, specifically the ability to give rise to all cell types found in a particular cancer sample. CSCs are therefore tumorigenic (tumor-forming), perhaps in contrast to other non-tumorigenic cancer cells. CSCs may generate tumors through the stem cell processes of self-renewal and differentiation into multiple cell types.".
- Cancer_stem_cell label "Cancer stem cell".
- Cancer_stem_cell label "Cellula staminale tumorale".
- Cancer_stem_cell label "Célula madre cancerosa".
- Cancer_stem_cell label "Krebsstammzelle".
- Cancer_stem_cell label "Rakowe komórki macierzyste".
- Cancer_stem_cell label "خلية جذعية سرطانية".
- Cancer_stem_cell label "がん幹細胞".
- Cancer_stem_cell label "癌幹細胞".
- Cancer_stem_cell sameAs Nádorová_kmenová_buňka.
- Cancer_stem_cell sameAs Krebsstammzelle.
- Cancer_stem_cell sameAs Célula_madre_cancerosa.
- Cancer_stem_cell sameAs Cellula_staminale_tumorale.
- Cancer_stem_cell sameAs がん幹細胞.
- Cancer_stem_cell sameAs Rakowe_komórki_macierzyste.
- Cancer_stem_cell sameAs m.07dw84.
- Cancer_stem_cell sameAs Q1638475.
- Cancer_stem_cell sameAs Q1638475.
- Cancer_stem_cell sameAs Cancer_stem_cell.
- Cancer_stem_cell wasDerivedFrom Cancer_stem_cell?oldid=604773128.
- Cancer_stem_cell depiction Cancer_stem_cells_text_resized.svg.
- Cancer_stem_cell isPrimaryTopicOf Cancer_stem_cell.