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- Cangrelor abstract "Cangrelor is a P2Y12 inhibitor under investigation as an antiplatelet drug for intravenous application. Some P2Y12 inhibitors are used clinically as effective inhibitors of adenosine diphosphate-mediated platelet activation and aggregation. Unlike clopidogrel (Plavix), which is a prodrug, cangrelor is an active drug not requiring metabolic conversion.Poor interim results led to the abandonment of the two CHAMPION clinical trials in mid-2009. The BRIDGE study, for short term use prior to surgery, continues. The CHAMPION PHOENIX trial was a randomized study of over 11,000 patients published in 2013. It found usefulness of cangrelor in patients getting cardiac stents. Compared with clopidogrel given around the time of stenting, intravenous ADP-receptor blockade with cangrelor significantly reduced the rate of stent thrombosis and myocardial infarction. Reviewers have questioned the methodology of the trial.".
- Cangrelor fdaUniiCode "6AQ1Y404U7".
- Cangrelor iupacName "[dichloro-[[[(2R,3S,4R,5R)-3,4-dihydroxy-5-[6-(2-methylsulfanylethylamino)-2-(3,3,3-trifluoropropylsulfanyl)purin-9-yl]oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]methyl]phosphonic acid".
- Cangrelor thumbnail Cangrelor.png?width=300.
- Cangrelor wikiPageID "23181077".
- Cangrelor wikiPageRevisionID "600315014".
- Cangrelor hasPhotoCollection Cangrelor.
- Cangrelor imagefile "Cangrelor.png".
- Cangrelor imagesize "200".
- Cangrelor iupacname "[dichloro-[[[-3,4-dihydroxy-5-[6--2-purin-9-yl]oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]methyl]phosphonic acid".
- Cangrelor unii "6".
- Cangrelor verifiedfields "changed".
- Cangrelor verifiedrevid "443628325".
- Cangrelor watchedfields "changed".
- Cangrelor subject Category:ADP_receptor_inhibitors.
- Cangrelor subject Category:Nucleotides.
- Cangrelor type Abstraction100002137.
- Cangrelor type Chemical114806838.
- Cangrelor type Compound114818238.
- Cangrelor type Ester114850483.
- Cangrelor type Material114580897.
- Cangrelor type Matter100020827.
- Cangrelor type Nucleotide114964590.
- Cangrelor type Nucleotides.
- Cangrelor type OrganicCompound114727670.
- Cangrelor type Part113809207.
- Cangrelor type PhysicalEntity100001930.
- Cangrelor type Relation100031921.
- Cangrelor type Substance100019613.
- Cangrelor type ChemicalCompound.
- Cangrelor type ChemicalSubstance.
- Cangrelor type ChemicalSubstanceType.
- Cangrelor type ChemicalObject.
- Cangrelor type Thing.
- Cangrelor comment "Cangrelor is a P2Y12 inhibitor under investigation as an antiplatelet drug for intravenous application. Some P2Y12 inhibitors are used clinically as effective inhibitors of adenosine diphosphate-mediated platelet activation and aggregation. Unlike clopidogrel (Plavix), which is a prodrug, cangrelor is an active drug not requiring metabolic conversion.Poor interim results led to the abandonment of the two CHAMPION clinical trials in mid-2009.".
- Cangrelor label "Cangrelor".
- Cangrelor label "Cangrelor".
- Cangrelor label "Cangrelor".
- Cangrelor sameAs Cangrelor.
- Cangrelor sameAs Cangrelor.
- Cangrelor sameAs m.064lcz8.
- Cangrelor sameAs Q3655338.
- Cangrelor sameAs Q3655338.
- Cangrelor sameAs Cangrelor.
- Cangrelor wasDerivedFrom Cangrelor?oldid=600315014.
- Cangrelor depiction Cangrelor.png.
- Cangrelor isPrimaryTopicOf Cangrelor.