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- Capromorelin abstract "Capromorelin (CP-424,391) is an investigational medication developed by the Pfizer drug company. It functions as a growth hormone secretagogue and ghrelin mimetic which causes the body to secrete human growth hormone in a way usually seen at puberty and in young adulthood. Initial studies have shown the drug to directly raise insulin growth factor 1 (IGF-1) and growth hormone levels.The drug is being considered for its therapeutic value in aging adults because elderly people have much lower levels of growth hormone and less lean muscle mass, which can result in weakness and frailty.In a one-year treatment trial (starting 1999) with 395 seniors between 65 and 84 years old, patients who received the drug gained an average of 3 lb (1.4 kg) in lean body mass in the first six months and also were better able to walk in a straight line in a test of balance, strength and coordination. After 12 months, patients receiving capromorelin also had an improved ability to climb stairs, however the results were not good enough to continue the trial for the 2nd planned year.Capromorelin, however, has not been approved by major regulatory bodies such as the World Health Organization, the European Medicines Agency or the United States FDA. In the U.S. at least, approval is not expected to be forthcoming any time soon, because the FDA does not consider aging a disease, and so requires extraordinary evidence of benefit and non-toxicity to approve a drug for use as an anti-aging agent.".
- Capromorelin atcPrefix "none".
- Capromorelin casNumber "193273-66-4".
- Capromorelin fdaUniiCode "0MQ44VUN84".
- Capromorelin iupacName "N-[(2R)-1-[(3aR)-2-methyl-3-oxo-3a-(phenylmethyl)-6,7-dihydro-4H-pyrazolo[4,3-c]pyridin-5-yl]-1-oxo-3-(phenylmethoxy)propan-2-yl]-2-amino-2-methylpropanamide".
- Capromorelin pubchem "216208".
- Capromorelin thumbnail Capromorelin_skeletal.svg?width=300.
- Capromorelin wikiPageExternalLink merriam.htm.
- Capromorelin wikiPageExternalLink merck.com.
- Capromorelin wikiPageExternalLink pfizer.com.
- Capromorelin wikiPageExternalLink www.capromorelin.biz.
- Capromorelin wikiPageExternalLink www.capromorelin.info.
- Capromorelin wikiPageExternalLink search;jsessionid=08C2FDEE53E3C72A975363B0DD328055?term=capromorelin&submit=Search.
- Capromorelin wikiPageID "7664447".
- Capromorelin wikiPageRevisionID "544577664".
- Capromorelin atcPrefix "none".
- Capromorelin c "28".
- Capromorelin casNumber "193273".
- Capromorelin chembl "113313".
- Capromorelin chemspiderid "187411".
- Capromorelin eliminationHalfLife "8640.0".
- Capromorelin h "35".
- Capromorelin hasPhotoCollection Capromorelin.
- Capromorelin iupacName "N-[-1-[-2-methyl-3-oxo-3a--6,7-dihydro-4H-pyrazolo[4,3-c]pyridin-5-yl]-1-oxo-3-propan-2-yl]-2-amino-2-methylpropanamide".
- Capromorelin molecularWeight "505.609".
- Capromorelin n "5".
- Capromorelin o "4".
- Capromorelin pubchem "216208".
- Capromorelin smiles "CCN".
- Capromorelin stdinchi "1".
- Capromorelin stdinchikey "KVLLHLWBPNCVNR-SKCUWOTOSA-N".
- Capromorelin unii "0".
- Capromorelin verifiedfields "changed".
- Capromorelin verifiedrevid "464366037".
- Capromorelin subject Category:Growth_hormone_secretagogues.
- Capromorelin type Drug.
- Capromorelin type DrugProduct.
- Capromorelin type FunctionalSubstance.
- Capromorelin comment "Capromorelin (CP-424,391) is an investigational medication developed by the Pfizer drug company. It functions as a growth hormone secretagogue and ghrelin mimetic which causes the body to secrete human growth hormone in a way usually seen at puberty and in young adulthood.".
- Capromorelin label "Capromorelin".
- Capromorelin sameAs m.02687yk.
- Capromorelin sameAs Q5036299.
- Capromorelin sameAs Q5036299.
- Capromorelin wasDerivedFrom Capromorelin?oldid=544577664.
- Capromorelin depiction Capromorelin_skeletal.svg.
- Capromorelin isPrimaryTopicOf Capromorelin.