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- Casokefamide abstract "Casokefamide (INN), also known as β-casomorphin 4027 (β-CM-4027) and [D-Ala2,4,Tyr5]-β-casomorphin-5-amide, is a peripherally-specific, synthetic opioid pentapeptide with the amino acid sequence Tyr-D-Ala-Phe-D-Ala-Tyr-NH2. Derived from the β-casomorphin sequence, it was designed with the intention of improving resistance to digestive enzymes so that it could potentially be used as an antidiarrheal medicine. Unlike other casomorphins, which are generally selective μ-opioid receptor agonists, casokefamide binds to both the μ- and δ-opioid receptors. In a clinical study, casokefamide was found to be effective via the oral route for the treatment of chronic diarrhea, and did not produce any side effects. However, further clinical development was not pursued and it was never marketed.".
- Casokefamide atcPrefix "None".
- Casokefamide casNumber "98815-38-4".
- Casokefamide iupacName "(L)-tyrosyl-(D)-alanyl-(L)-phenylalanyl-(D)-alanyl-(L)-tyrosinamide".
- Casokefamide pubchem "5464104".
- Casokefamide thumbnail Casokefamide.svg?width=300.
- Casokefamide wikiPageID "35631023".
- Casokefamide wikiPageRevisionID "599129667".
- Casokefamide atcPrefix "None".
- Casokefamide c "33".
- Casokefamide casNumber "98815".
- Casokefamide chemspiderid "4576538".
- Casokefamide h "40".
- Casokefamide hasPhotoCollection Casokefamide.
- Casokefamide inchi "1".
- Casokefamide inchikey "XDRHVZLDLNGKLM-FLVVDCEDBR".
- Casokefamide iupacName "(L)-tyrosyl-(D)-alanyl-(L)-phenylalanyl-(D)-alanyl-(L)-tyrosinamide".
- Casokefamide molecularWeight "632.707".
- Casokefamide n "6".
- Casokefamide o "7".
- Casokefamide pubchem "5464104".
- Casokefamide smiles "O=C[C@@H]Cc3ccccc3".
- Casokefamide stdinchi "1".
- Casokefamide stdinchikey "XDRHVZLDLNGKLM-FLVVDCEDSA-N".
- Casokefamide subject Category:Amides.
- Casokefamide subject Category:Antidiarrhoeals.
- Casokefamide subject Category:Opioid_peptides.
- Casokefamide type Abstraction100002137.
- Casokefamide type Amide114724264.
- Casokefamide type Amides.
- Casokefamide type Chemical114806838.
- Casokefamide type Compound114818238.
- Casokefamide type Material114580897.
- Casokefamide type Matter100020827.
- Casokefamide type OrganicCompound114727670.
- Casokefamide type Part113809207.
- Casokefamide type Peptide114743046.
- Casokefamide type Peptides.
- Casokefamide type PhysicalEntity100001930.
- Casokefamide type Relation100031921.
- Casokefamide type Substance100019613.
- Casokefamide type Drug.
- Casokefamide type FunctionalSubstance.
- Casokefamide comment "Casokefamide (INN), also known as β-casomorphin 4027 (β-CM-4027) and [D-Ala2,4,Tyr5]-β-casomorphin-5-amide, is a peripherally-specific, synthetic opioid pentapeptide with the amino acid sequence Tyr-D-Ala-Phe-D-Ala-Tyr-NH2. Derived from the β-casomorphin sequence, it was designed with the intention of improving resistance to digestive enzymes so that it could potentially be used as an antidiarrheal medicine.".
- Casokefamide label "Casokefamide".
- Casokefamide sameAs m.0jkywk1.
- Casokefamide sameAs Q5048995.
- Casokefamide sameAs Q5048995.
- Casokefamide sameAs Casokefamide.
- Casokefamide wasDerivedFrom Casokefamide?oldid=599129667.
- Casokefamide depiction Casokefamide.svg.
- Casokefamide isPrimaryTopicOf Casokefamide.