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- Caspase-activated_DNase abstract "Caspase-activated DNase (CAD) is an endonuclease found in the extrinsic apoptotic pathway of cells. In the absence of apoptotic signals, CAD is inhibited by ICAD (Inhibitor of Caspase Activated DNase). During apoptosis, however, caspase 3 cleaves ICAD, thereby freeing CAD to cleave the DNA at random sections of linker DNA between individual nucleosomes. These sections are the only parts of the DNA that are fully exposed when the DNA is condensed to chromatin, the standard form of DNA in vivo. Cleavage by CAD results in DNA fragments with lengths that are multiples of 180 bp, an effect known as apoptotic DNA fragmentation.".
- Caspase-activated_DNase wikiPageExternalLink watch?v=LCEVqrkPKlA.
- Caspase-activated_DNase wikiPageID "27283311".
- Caspase-activated_DNase wikiPageRevisionID "590864766".
- Caspase-activated_DNase hasPhotoCollection Caspase-activated_DNase.
- Caspase-activated_DNase subject Category:Apoptosis.
- Caspase-activated_DNase subject Category:EC_3.1.
- Caspase-activated_DNase subject Category:Human_proteins.
- Caspase-activated_DNase subject Category:Nucleases.
- Caspase-activated_DNase type Abstraction100002137.
- Caspase-activated_DNase type Chemical114806838.
- Caspase-activated_DNase type Compound114818238.
- Caspase-activated_DNase type HumanProteins.
- Caspase-activated_DNase type Macromolecule114944888.
- Caspase-activated_DNase type Material114580897.
- Caspase-activated_DNase type Matter100020827.
- Caspase-activated_DNase type Molecule114682133.
- Caspase-activated_DNase type OrganicCompound114727670.
- Caspase-activated_DNase type Part113809207.
- Caspase-activated_DNase type PhysicalEntity100001930.
- Caspase-activated_DNase type Protein114728724.
- Caspase-activated_DNase type Relation100031921.
- Caspase-activated_DNase type Substance100019613.
- Caspase-activated_DNase type Thing100002452.
- Caspase-activated_DNase type Unit109465459.
- Caspase-activated_DNase comment "Caspase-activated DNase (CAD) is an endonuclease found in the extrinsic apoptotic pathway of cells. In the absence of apoptotic signals, CAD is inhibited by ICAD (Inhibitor of Caspase Activated DNase). During apoptosis, however, caspase 3 cleaves ICAD, thereby freeing CAD to cleave the DNA at random sections of linker DNA between individual nucleosomes. These sections are the only parts of the DNA that are fully exposed when the DNA is condensed to chromatin, the standard form of DNA in vivo.".
- Caspase-activated_DNase label "Caspase-activated DNase".
- Caspase-activated_DNase label "DNasi attivata da caspasi".
- Caspase-activated_DNase sameAs DNasi_attivata_da_caspasi.
- Caspase-activated_DNase sameAs m.0bwh3y6.
- Caspase-activated_DNase sameAs Q5049047.
- Caspase-activated_DNase sameAs Q5049047.
- Caspase-activated_DNase sameAs Caspase-activated_DNase.
- Caspase-activated_DNase wasDerivedFrom Caspase-activated_DNase?oldid=590864766.
- Caspase-activated_DNase isPrimaryTopicOf Caspase-activated_DNase.