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- Caspase_6 abstract "Caspase-6 is an enzyme that in humans is encoded by the CASP6 gene.CASP6 orthologs have been identified in numerous mammals for which complete genome data are available. Unique orthologs are also present in birds, lizards, lissamphibians, and teleosts.This gene encodes a protein that is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes that undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein is processed by caspases 7, 8 and 10, and is thought to function as a downstream enzyme in the caspase activation cascade. Caspase 6 can also undergo self-processing without other members of the caspase family. Alternative splicing of this gene results in two transcript variants that encode different isoforms.".
- Caspase_6 entrezgene "839".
- Caspase_6 wikiPageExternalLink merops.cgi?id=C14.005.
- Caspase_6 wikiPageID "14120647".
- Caspase_6 wikiPageRevisionID "590864933".
- Caspase_6 hasPhotoCollection Caspase_6.
- Caspase_6 requireManualInspection "no".
- Caspase_6 summaryText "This gene encodes a protein that is a member of the cysteine-aspartic acid protease family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes that undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein is processed by caspases 7, 8 and 10, and is thought to function as a downstream enzyme in the caspase activation cascade. Caspase 6 can also undergo self-processing without other members of the caspase family. Alternative splicing of this gene results in two transcript variants that encode different isoforms.".
- Caspase_6 updateCitations "yes".
- Caspase_6 updatePage "yes".
- Caspase_6 updateProteinBox "yes".
- Caspase_6 updateSummary "no".
- Caspase_6 type Biomolecule.
- Caspase_6 type Protein.
- Caspase_6 type BiologicalObject.
- Caspase_6 comment "Caspase-6 is an enzyme that in humans is encoded by the CASP6 gene.CASP6 orthologs have been identified in numerous mammals for which complete genome data are available. Unique orthologs are also present in birds, lizards, lissamphibians, and teleosts.This gene encodes a protein that is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis.".
- Caspase_6 label "Caspase 6".
- Caspase_6 label "Caspase 6".
- Caspase_6 sameAs Caspase_6.
- Caspase_6 sameAs m.03cv6pk.
- Caspase_6 sameAs Q5049055.
- Caspase_6 sameAs Q5049055.
- Caspase_6 wasDerivedFrom Caspase_6?oldid=590864933.
- Caspase_6 isPrimaryTopicOf Caspase_6.