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- Cediranib abstract "Cediranib (tentative trade name Recentin), also known as AZD2171, is a potent inhibitor of vascular endothelial growth factor (VEGF) receptor tyrosine kinases.It is being developed by AstraZeneca as a possible anti-cancer chemotherapeutic agent for oral administration.Beginning in 2007, it underwent Phase I clinical trials for the treatment of non-small cell lung cancer, kidney cancer, and colorectal cancer in adults, as well as tumors of the central nervous system in children. Phase I trials of interactions with other drugs used in cancer treatment were also undertaken.On February 27, 2008, AstraZeneca announced that the use of Cediranib in non-small cell lung cancer will not progress into phase III after failing to meet its main goal.On 8 March 2010, AstraZeneca issued a press-release stating that Cediranib had failed Phase III clinical trials for use in first-line metastatic colorectal cancer when it was compared clinically with the market-leader bevacizumab.As of November 2012, it was being assessed in double-blind studies for the treatment of methylated Glioblastoma Multiforme at the University of Washington Medical Center at a 20 mg daily dose.".
- Cediranib atcPrefix "none".
- Cediranib casNumber "288383-20-0".
- Cediranib fdaUniiCode "NQU9IPY4K9".
- Cediranib iupacName "4-[(4-fluoro-2-methyl-1H-indol-5-yl)oxy]-6-methoxy-7-[3-(pyrrolidin-1-yl)propoxy]quinazoline".
- Cediranib pubchem "9933475".
- Cediranib thumbnail AZD2171.svg?width=300.
- Cediranib wikiPageExternalLink 15602_15632_9_3_1.aspx.
- Cediranib wikiPageID "10129400".
- Cediranib wikiPageRevisionID "600271320".
- Cediranib atcPrefix "none".
- Cediranib c "25".
- Cediranib casNumber "288383".
- Cediranib chemspiderid "8109103".
- Cediranib eliminationHalfLife "126000.0".
- Cediranib f "1".
- Cediranib h "27".
- Cediranib hasPhotoCollection Cediranib.
- Cediranib inchi "1".
- Cediranib inchikey "XXJWYDDUDKYVKI-UHFFFAOYAE".
- Cediranib iupacName "4".
- Cediranib molecularWeight "450.505".
- Cediranib n "4".
- Cediranib o "3".
- Cediranib pubchem "9933475".
- Cediranib routesOfAdministration "Oral".
- Cediranib smiles "Cc4nc5ccccc5c4".
- Cediranib stdinchi "1".
- Cediranib stdinchikey "XXJWYDDUDKYVKI-UHFFFAOYSA-N".
- Cediranib unii "NQU9IPY4K9".
- Cediranib verifiedfields "changed".
- Cediranib verifiedrevid "449572361".
- Cediranib watchedfields "changed".
- Cediranib subject Category:Experimental_cancer_drugs.
- Cediranib subject Category:Indoles.
- Cediranib subject Category:Organofluorides.
- Cediranib subject Category:Phenol_ethers.
- Cediranib subject Category:Pyrrolidines.
- Cediranib subject Category:Quinazolines.
- Cediranib subject Category:Receptor_tyrosine_kinase_inhibitors.
- Cediranib type Agent114778436.
- Cediranib type Antineoplastic102722458.
- Cediranib type CausalAgent100007347.
- Cediranib type CytotoxicDrug103157987.
- Cediranib type Drug103247620.
- Cediranib type ExperimentalCancerDrugs.
- Cediranib type Matter100020827.
- Cediranib type Medicine103740161.
- Cediranib type PhysicalEntity100001930.
- Cediranib type ReceptorTyrosineKinaseInhibitors.
- Cediranib type Substance100020090.
- Cediranib type TyrosineKinaseInhibitor104506005.
- Cediranib type Drug.
- Cediranib type DrugProduct.
- Cediranib type FunctionalSubstance.
- Cediranib comment "Cediranib (tentative trade name Recentin), also known as AZD2171, is a potent inhibitor of vascular endothelial growth factor (VEGF) receptor tyrosine kinases.It is being developed by AstraZeneca as a possible anti-cancer chemotherapeutic agent for oral administration.Beginning in 2007, it underwent Phase I clinical trials for the treatment of non-small cell lung cancer, kidney cancer, and colorectal cancer in adults, as well as tumors of the central nervous system in children.".
- Cediranib label "Cediranib".
- Cediranib sameAs m.02q2rq_.
- Cediranib sameAs Q5057052.
- Cediranib sameAs Q5057052.
- Cediranib sameAs Cediranib.
- Cediranib wasDerivedFrom Cediranib?oldid=600271320.
- Cediranib depiction AZD2171.svg.
- Cediranib isPrimaryTopicOf Cediranib.