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- Bse634I abstract "In molecular biology, the Cfr10I/Bse634I family of restriction endonucleases includes the type II restriction endonucleases Cfr10I and Bse634I. They exhibit a conserved tetrameric architecture that is of functional importance, wherein two dimers are arranged, back-to-back, with their putative DNA-binding clefts facing opposite directions. These clefts are formed between two monomers that interact, mainly via hydrophobic interactions supported by a few hydrogen bonds, to form a U-shaped dimer. Each monomer is folded to form a compact alpha-beta structure, whose core is made up of a five-stranded mixed beta-sheet. The monomer may be split into separate N-terminal and C-terminal subdomains at a hinge located in helix alpha3. Both Cfr10I and Bse634I recognise the double-stranded sequence RCCGGY and cleave after the purine R.Recognition sequence Cut5' RCCGGY 5' ---R CCGGY--- 3' 3' YGGCCR 3' ---YGGCC R--- 5'".
- Bse634I symbol "Bse634I".
- Bse634I thumbnail PDB_1cfr_EBI.jpg?width=300.
- Bse634I wikiPageID "32170974".
- Bse634I wikiPageRevisionID "601848873".
- Bse634I caption "crystal structure of citrobacter freundii restriction endonuclease cfr10i at 2.15 angstroms resolution.".
- Bse634I hasPhotoCollection Bse634I.
- Bse634I interpro "IPR012415".
- Bse634I name "Bse634I".
- Bse634I pfam "PF07832".
- Bse634I symbol "Bse634I".
- Bse634I subject Category:Bacterial_enzymes.
- Bse634I subject Category:EC_3.1.
- Bse634I subject Category:Molecular_biology.
- Bse634I subject Category:Protein_domains.
- Bse634I subject Category:Restriction_enzymes.
- Bse634I type Biomolecule.
- Bse634I type Protein.
- Bse634I type BiologicalObject.
- Bse634I comment "In molecular biology, the Cfr10I/Bse634I family of restriction endonucleases includes the type II restriction endonucleases Cfr10I and Bse634I. They exhibit a conserved tetrameric architecture that is of functional importance, wherein two dimers are arranged, back-to-back, with their putative DNA-binding clefts facing opposite directions. These clefts are formed between two monomers that interact, mainly via hydrophobic interactions supported by a few hydrogen bonds, to form a U-shaped dimer.".
- Bse634I label "Cfr10I/Bse634I".
- Bse634I sameAs m.0gx19gp.
- Bse634I sameAs Q5065861.
- Bse634I sameAs Q5065861.
- Bse634I wasDerivedFrom Bse634I?oldid=601848873.
- Bse634I depiction PDB_1cfr_EBI.jpg.
- Bse634I isPrimaryTopicOf Bse634I.