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- Chloral_hydrate abstract "Chloral hydrate is an organic compound with the formula C2H3Cl3O2. It is a colourless solid. It was once used as sedative and hypnotic drug. It remains a useful laboratory chemical reagent and precursor. It is derived from chloral (trichloroacetaldehyde) by the addition of one equivalent of water.It was discovered through the chlorination (halogenation) of ethanol in 1832 by Justus von Liebig in Gießen. Its sedative properties were first published in 1869 and subsequently, because of its easy synthesis, its use was widespread. It was widely used recreationally and misprescribed in the late 19th century. Chloral hydrate is soluble in both water and alcohol, readily forming concentrated solutions. A solution of chloral hydrate in alcohol called "knockout drops" was used to prepare a Mickey Finn. More reputable uses of chloral hydrate include its use as a clearing agent for chitin and fibers and as a key ingredient in Hoyer's mounting medium, which is used to prepare permanent or semi-permanent microscope slides of small organisms, histological sections, and chromosome squashes. Because of its status as a regulated substance, chloral hydrate can be difficult to obtain. To cope with procurement problems, Rutgers scientists have developed a substitute for chloral hydrate for use in microscopy, known as Visikol, which has been shown to be an effective replacement for chloral hydrate for clearing plant specimens.It is, together with chloroform, a minor side-product of the chlorination of water when organic residues such as humic acids are present. It has been detected in drinking water at concentrations of up to 100 micrograms per litre (µg/L) but concentrations are normally found to be below 10 µg/L. Levels are generally found to be higher in surface water than in ground water.Chloral hydrate has not been approved by the FDA in the United States or the EMA in the European Union for any medical indication and is on the list of unapproved drugs that is still prescribed by clinicians. Usage of the drug as a sedative or hypnotic may carry some risk given the lack of clinical trials.".
- Chloral_hydrate iupacName "2,2,2-trichloroethane-1,1-diol".
- Chloral_hydrate thumbnail Chloral-hydrate-montage.png?width=300.
- Chloral_hydrate wikiPageExternalLink chloral_hydrate.html.
- Chloral_hydrate wikiPageID "276390".
- Chloral_hydrate wikiPageRevisionID "605437678".
- Chloral_hydrate hasPhotoCollection Chloral_hydrate.
- Chloral_hydrate imagefile "Chloral-hydrate-montage.png".
- Chloral_hydrate imagesize "250".
- Chloral_hydrate iupacname "222".
- Chloral_hydrate othernames "Tradenames: Aquachloral, Novo-Chlorhydrate, Somnos, Noctec, Somnote".
- Chloral_hydrate othernames "Trichloroacetaldehyde monohydrate".
- Chloral_hydrate verifiedrevid "443513096".
- Chloral_hydrate watchedfields "changed".
- Chloral_hydrate subject Category:Aldehydes.
- Chloral_hydrate subject Category:Hydrates.
- Chloral_hydrate subject Category:Hypnotics.
- Chloral_hydrate subject Category:Organochlorides.
- Chloral_hydrate subject Category:Prodrugs.
- Chloral_hydrate subject Category:Sedatives.
- Chloral_hydrate type ChemicalCompound.
- Chloral_hydrate type ChemicalSubstance.
- Chloral_hydrate type ChemicalSubstanceType.
- Chloral_hydrate type ChemicalObject.
- Chloral_hydrate type Thing.
- Chloral_hydrate comment "Chloral hydrate is an organic compound with the formula C2H3Cl3O2. It is a colourless solid. It was once used as sedative and hypnotic drug. It remains a useful laboratory chemical reagent and precursor. It is derived from chloral (trichloroacetaldehyde) by the addition of one equivalent of water.It was discovered through the chlorination (halogenation) of ethanol in 1832 by Justus von Liebig in Gießen.".
- Chloral_hydrate label "2,2,2-tricloro-1,1-etandiolo".
- Chloral_hydrate label "Chloraalhydraat".
- Chloral_hydrate label "Chloral hydrate".
- Chloral_hydrate label "Chloralhydrat".
- Chloral_hydrate label "Hidrato de cloral".
- Chloral_hydrate label "Hidrato de cloral".
- Chloral_hydrate label "Hydrate de chloral".
- Chloral_hydrate label "Wodzian chloralu".
- Chloral_hydrate label "Хлоральгидрат".
- Chloral_hydrate label "هيدرات الكلورال".
- Chloral_hydrate label "抱水クロラール".
- Chloral_hydrate label "水合氯醛".
- Chloral_hydrate sameAs Chloralhydrát.
- Chloral_hydrate sameAs Chloralhydrat.
- Chloral_hydrate sameAs Hidrato_de_cloral.
- Chloral_hydrate sameAs Hydrate_de_chloral.
- Chloral_hydrate sameAs 2,2,2-tricloro-1,1-etandiolo.
- Chloral_hydrate sameAs 抱水クロラール.
- Chloral_hydrate sameAs Chloraalhydraat.
- Chloral_hydrate sameAs Wodzian_chloralu.
- Chloral_hydrate sameAs Hidrato_de_cloral.
- Chloral_hydrate sameAs m.01pcyw.
- Chloral_hydrate sameAs Q412340.
- Chloral_hydrate sameAs Q412340.
- Chloral_hydrate sameAs DB01563.
- Chloral_hydrate wasDerivedFrom Chloral_hydrate?oldid=605437678.
- Chloral_hydrate depiction Chloral-hydrate-montage.png.
- Chloral_hydrate isPrimaryTopicOf Chloral_hydrate.