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- Chloramphenicol abstract "Chloramphenicol (INN) is an antibiotic useful for the treatment of a number of bacterial infections. It is a bacteriostatic and became available in 1949. It is considered a prototypical broad-spectrum antibiotic, alongside the tetracyclines, and as it is both cheap and easy to manufacture it is frequently an antibiotic of choice in the developing world.Chloramphenicol, also known as chlornitromycin, is effective against a wide variety of Gram-positive and Gram-negative bacteria, including most anaerobic organisms. Due to resistance and safety concerns, it is no longer a first-line agent for any infection in developed nations, with the notable exception of topical treatment of bacterial conjunctivitis. Nevertheless, the global problem of advancing bacterial resistance to newer drugs has led to renewed interest in its use. In low-income countries, chloramphenicol is still widely used because it is inexpensive and readily available.The most serious adverse effect associated with chloramphenicol treatment is bone marrow toxicity, which may occur in two distinct forms: bone marrow suppression, which is a direct toxic effect of the drug and is usually reversible, and aplastic anemia, which is idiosyncratic (rare, unpredictable, and unrelated to dose) and generally fatal.Use of intravenous chloramphenicol has also been associated with gray baby syndrome, a phenomenon resulting from newborn infants' inability to metabolize chloramphenicol in the body. Other less serious reactions include fever, rashes, headache and confusion. Prescription use is usually done in association with monitoring of a patient's complete blood count. The drug should be discontinued upon appearance of reticulocytopenia, leukopenia, thrombocytopenia, anemia or any other abnormal blood study findings attributable to chloramphenicol.It is on the World Health Organization's List of Essential Medicines, a list of the most important medications needed in a basic health system.".
- Chloramphenicol atcPrefix "D06".
- Chloramphenicol atcSuffix "AX02".
- Chloramphenicol bioavailability "75.0".
- Chloramphenicol casNumber "56-75-7".
- Chloramphenicol chEBI "17698".
- Chloramphenicol drugbank "DB00446".
- Chloramphenicol fdaUniiCode "66974FR9Q1".
- Chloramphenicol iupacName "2,2-dichloro-N-[1,3-dihydroxy-1-(4-nitrophenyl)propan-2-yl]acetamide".
- Chloramphenicol pubchem "298".
- Chloramphenicol thumbnail Chloramphenicol-2D-skeletal.svg?width=300.
- Chloramphenicol wikiPageExternalLink ?ligand=CLM.
- Chloramphenicol wikiPageExternalLink chloro.htm.
- Chloramphenicol wikiPageID "6346".
- Chloramphenicol wikiPageRevisionID "606261683".
- Chloramphenicol atcPrefix "D06".
- Chloramphenicol atcSuffix "AX02".
- Chloramphenicol bioavailability "75".
- Chloramphenicol c "11".
- Chloramphenicol casNumber "56".
- Chloramphenicol chebi "17698".
- Chloramphenicol chembl "130".
- Chloramphenicol chemspiderid "5744".
- Chloramphenicol cl "2".
- Chloramphenicol drugbank "DB00446".
- Chloramphenicol eliminationHalfLife "-11880.0".
- Chloramphenicol excretion "Renal , faeces".
- Chloramphenicol h "12".
- Chloramphenicol hasPhotoCollection Chloramphenicol.
- Chloramphenicol image "Chloramphenicol-3D-vdW.png".
- Chloramphenicol inchi "1".
- Chloramphenicol iupacName "22".
- Chloramphenicol kegg "D00104".
- Chloramphenicol legalAu "S4".
- Chloramphenicol legalCa "Rx-only".
- Chloramphenicol legalUk "POM".
- Chloramphenicol legalUs "Rx-only".
- Chloramphenicol licenceUs "Chloramphenicol".
- Chloramphenicol medlineplus "a608008".
- Chloramphenicol metabolism Liver.
- Chloramphenicol molecularWeight "323.132".
- Chloramphenicol n "2".
- Chloramphenicol o "5".
- Chloramphenicol pregnancyAu "A".
- Chloramphenicol pregnancyUs "C".
- Chloramphenicol proteinBound "60.0".
- Chloramphenicol pubchem "298".
- Chloramphenicol routesOfAdministration "Topical , oral, IV, IM".
- Chloramphenicol smiles "c1cc[N+][O-]".
- Chloramphenicol stdinchi "1".
- Chloramphenicol stdinchikey "WIIZWVCIJKGZOK-RKDXNWHRSA-N".
- Chloramphenicol unii "66974".
- Chloramphenicol verifiedrevid "443513464".
- Chloramphenicol watchedfields "changed".
- Chloramphenicol subject Category:Acetamides.
- Chloramphenicol subject Category:Amphenicols.
- Chloramphenicol subject Category:Diols.
- Chloramphenicol subject Category:Halogen-containing_natural_products.
- Chloramphenicol subject Category:IARC_Group_2A_carcinogens.
- Chloramphenicol subject Category:Nitrobenzenes.
- Chloramphenicol subject Category:Organochlorides.
- Chloramphenicol subject Category:Otologicals.
- Chloramphenicol subject Category:Phenethylamines.
- Chloramphenicol subject Category:World_Health_Organization_essential_medicines.
- Chloramphenicol type Drug.
- Chloramphenicol type DrugProduct.
- Chloramphenicol type FunctionalSubstance.
- Chloramphenicol comment "Chloramphenicol (INN) is an antibiotic useful for the treatment of a number of bacterial infections. It is a bacteriostatic and became available in 1949.".
- Chloramphenicol label "Chlooramfenicol".
- Chloramphenicol label "Chloramfenikol".
- Chloramphenicol label "Chloramphenicol".
- Chloramphenicol label "Chloramphenicol".
- Chloramphenicol label "Chloramphénicol".
- Chloramphenicol label "Cloramfenicolo".
- Chloramphenicol label "Cloranfenicol".
- Chloramphenicol label "Cloranfenicol".
- Chloramphenicol label "Хлорамфеникол".
- Chloramphenicol label "كلورامفينيكول".
- Chloramphenicol label "クロラムフェニコール".
- Chloramphenicol label "氯霉素".
- Chloramphenicol sameAs Chloramfenikol.
- Chloramphenicol sameAs Chloramphenicol.
- Chloramphenicol sameAs Cloranfenicol.
- Chloramphenicol sameAs Kloranfenikol.
- Chloramphenicol sameAs Chloramphénicol.
- Chloramphenicol sameAs Cloramfenicolo.
- Chloramphenicol sameAs クロラムフェニコール.
- Chloramphenicol sameAs Chlooramfenicol.
- Chloramphenicol sameAs Chloramfenikol.
- Chloramphenicol sameAs Cloranfenicol.
- Chloramphenicol sameAs m.01whr.
- Chloramphenicol sameAs Q274515.
- Chloramphenicol sameAs Q274515.
- Chloramphenicol sameAs chloramphenicol.
- Chloramphenicol sameAs DB00446.
- Chloramphenicol wasDerivedFrom Chloramphenicol?oldid=606261683.
- Chloramphenicol depiction Chloramphenicol-2D-skeletal.svg.
- Chloramphenicol isPrimaryTopicOf Chloramphenicol.