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- Ciliary_neurotrophic_factor abstract "Ciliary neurotrophic factor is a protein that in humans is encoded by the CNTF gene.The protein encoded by this gene is a polypeptide hormone and nerve growth factor whose actions have mainly been studied in the nervous system where it promotes neurotransmitter synthesis and neurite outgrowth in certain neural populations including astrocytes. The protein is a potent survival factor for neurons and oligodendrocytes and may be relevant in reducing tissue destruction during inflammatory attacks. A mutation in this gene, which results in aberrant splicing, leads to ciliary neurotrophic factor deficiency, but this phenotype is not causally related to neurologic disease. In addition to the predominant monocistronic transcript originating from this locus, the gene is also co-transcribed with the upstream ZFP91 gene. Co-transcription from the two loci results in a transcript that contains a complete coding region for the zinc finger protein but lacks a complete coding region for ciliary neurotrophic factor.CNTF has also been shown to be expressed by cells on the bone surface, and to reduce the activity of bone forming cells, osteoblasts.".
- Ciliary_neurotrophic_factor entrezgene "1270".
- Ciliary_neurotrophic_factor wikiPageID "7330356".
- Ciliary_neurotrophic_factor wikiPageRevisionID "593766738".
- Ciliary_neurotrophic_factor hasPhotoCollection Ciliary_neurotrophic_factor.
- Ciliary_neurotrophic_factor summaryText "The protein encoded by this gene is a polypeptide hormone and nerve growth factor whose actions have mainly been studied in the nervous system where it promotes neurotransmitter synthesis and neurite outgrowth in certain neural populations including astrocytes. The protein is a potent survival factor for neurons and oligodendrocytes and may be relevant in reducing tissue destruction during inflammatory attacks. A mutation in this gene, which results in aberrant splicing, leads to ciliary neurotrophic factor deficiency, but this phenotype is not causally related to neurologic disease. In addition to the predominant monocistronic transcript originating from this locus, the gene is also co-transcribed with the upstream ZFP91 gene. Co-transcription from the two loci results in a transcript that contains a complete coding region for the zinc finger protein but lacks a complete coding region for ciliary neurotrophic factor.".
- Ciliary_neurotrophic_factor subject Category:Developmental_neuroscience.
- Ciliary_neurotrophic_factor subject Category:Neurotrophins.
- Ciliary_neurotrophic_factor subject Category:Peptide_hormones.
- Ciliary_neurotrophic_factor subject Category:Proteins.
- Ciliary_neurotrophic_factor type Abstraction100002137.
- Ciliary_neurotrophic_factor type BodySubstance105263850.
- Ciliary_neurotrophic_factor type Chemical114806838.
- Ciliary_neurotrophic_factor type Compound114818238.
- Ciliary_neurotrophic_factor type Hormone105407119.
- Ciliary_neurotrophic_factor type LiquidBodySubstance105397468.
- Ciliary_neurotrophic_factor type Macromolecule114944888.
- Ciliary_neurotrophic_factor type Material114580897.
- Ciliary_neurotrophic_factor type Matter100020827.
- Ciliary_neurotrophic_factor type Molecule114682133.
- Ciliary_neurotrophic_factor type OrganicCompound114727670.
- Ciliary_neurotrophic_factor type Part113809207.
- Ciliary_neurotrophic_factor type PeptideHormones.
- Ciliary_neurotrophic_factor type PhysicalEntity100001930.
- Ciliary_neurotrophic_factor type Protein114728724.
- Ciliary_neurotrophic_factor type Proteins.
- Ciliary_neurotrophic_factor type Relation100031921.
- Ciliary_neurotrophic_factor type Secretion105404728.
- Ciliary_neurotrophic_factor type Substance100019613.
- Ciliary_neurotrophic_factor type Thing100002452.
- Ciliary_neurotrophic_factor type Unit109465459.
- Ciliary_neurotrophic_factor type Biomolecule.
- Ciliary_neurotrophic_factor type Protein.
- Ciliary_neurotrophic_factor type BiologicalObject.
- Ciliary_neurotrophic_factor comment "Ciliary neurotrophic factor is a protein that in humans is encoded by the CNTF gene.The protein encoded by this gene is a polypeptide hormone and nerve growth factor whose actions have mainly been studied in the nervous system where it promotes neurotransmitter synthesis and neurite outgrowth in certain neural populations including astrocytes. The protein is a potent survival factor for neurons and oligodendrocytes and may be relevant in reducing tissue destruction during inflammatory attacks.".
- Ciliary_neurotrophic_factor label "Ciliary neurotrophic factor".
- Ciliary_neurotrophic_factor sameAs m.025zcny.
- Ciliary_neurotrophic_factor sameAs Q5119950.
- Ciliary_neurotrophic_factor sameAs Q5119950.
- Ciliary_neurotrophic_factor sameAs Ciliary_neurotrophic_factor.
- Ciliary_neurotrophic_factor wasDerivedFrom Ciliary_neurotrophic_factor?oldid=593766738.
- Ciliary_neurotrophic_factor isPrimaryTopicOf Ciliary_neurotrophic_factor.