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- Cinacalcet abstract "Cinacalcet (INN) is a drug that acts as a calcimimetic (i.e. it mimics the action of calcium on tissues) by allosteric activation of the calcium-sensing receptor that is expressed in various human organ tissues. It is sold by Amgen under the trade name Sensipar in North America and Australia and as Mimpara in Europe. Cinacalcet is used to treat secondary hyperparathyroidism (elevated parathyroid hormone levels), a consequence of end-stage renal disease. Cinacalcet is also indicated for the treatment of hypercalcemia in patients with parathyroid carcinoma.Clinical trials conducted in the United States by Amgen to determine whether the drug is safe for children were halted by the FDA in February 2013 following the death of a 14-year-old patient.".
- Cinacalcet atcPrefix "H05".
- Cinacalcet atcSuffix "BX01".
- Cinacalcet bioavailability "20.0".
- Cinacalcet casNumber "226256-56-0".
- Cinacalcet chEBI "48390".
- Cinacalcet drugbank "DB01012".
- Cinacalcet fdaUniiCode "UAZ6V7728S".
- Cinacalcet iupacName "(R)-N-[1-(1-naphthyl)ethyl]-3-".
- Cinacalcet iupacName "[3-(trifluoromethyl)phenyl]propan-1-amine".
- Cinacalcet pubchem "156419".
- Cinacalcet thumbnail Cinacalcet_Structural_Formulae.png?width=300.
- Cinacalcet wikiPageExternalLink 0,3915,8207%7CCinacalcet,00.html.
- Cinacalcet wikiPageExternalLink a605004.html.
- Cinacalcet wikiPageExternalLink www.sensipar.com.
- Cinacalcet wikiPageExternalLink sensipar_pi.pdf.
- Cinacalcet wikiPageID "1903249".
- Cinacalcet wikiPageRevisionID "604688985".
- Cinacalcet atcPrefix "H05".
- Cinacalcet atcSuffix "BX01".
- Cinacalcet bioavailability "20".
- Cinacalcet bioavailability "Increases if taken with food".
- Cinacalcet c "22".
- Cinacalcet casNumber "226256".
- Cinacalcet chebi "48390".
- Cinacalcet chembl "1201284".
- Cinacalcet chemspiderid "137743".
- Cinacalcet drugbank "DB01012".
- Cinacalcet eliminationHalfLife "144000.0".
- Cinacalcet excretion "Renal and fecal".
- Cinacalcet f "3".
- Cinacalcet h "22".
- Cinacalcet hasPhotoCollection Cinacalcet.
- Cinacalcet image "Cinacalcet ball-and-stick.png".
- Cinacalcet inchi "1".
- Cinacalcet inchikey "VDHAWDNDOKGFTD-MRXNPFEDBJ".
- Cinacalcet iupacName "-N-[1-ethyl]-3-".
- Cinacalcet iupacName "[3-phenyl]propan-1-amine".
- Cinacalcet iupharLigand "3308".
- Cinacalcet kegg "D03504".
- Cinacalcet legalStatus "Rx-only".
- Cinacalcet licenceEu "Mimpara".
- Cinacalcet licenceUs "Cinacalcet".
- Cinacalcet medlineplus "a605004".
- Cinacalcet metabolism "Hepatic".
- Cinacalcet molecularWeight "357.412".
- Cinacalcet n "1".
- Cinacalcet pregnancyAu "B3".
- Cinacalcet pregnancyUs "C".
- Cinacalcet proteinBound "93".
- Cinacalcet pubchem "156419".
- Cinacalcet routesOfAdministration "Oral".
- Cinacalcet smiles "FCc1ccccCCCN[C@@H]C".
- Cinacalcet stdinchi "1".
- Cinacalcet stdinchikey "VDHAWDNDOKGFTD-MRXNPFEDSA-N".
- Cinacalcet unii "UAZ6V7728S".
- Cinacalcet verifiedfields "changed".
- Cinacalcet verifiedrevid "460037495".
- Cinacalcet subject Category:Systemic_hormonal_preparations.
- Cinacalcet type Drug.
- Cinacalcet type DrugProduct.
- Cinacalcet type FunctionalSubstance.
- Cinacalcet comment "Cinacalcet (INN) is a drug that acts as a calcimimetic (i.e. it mimics the action of calcium on tissues) by allosteric activation of the calcium-sensing receptor that is expressed in various human organ tissues. It is sold by Amgen under the trade name Sensipar in North America and Australia and as Mimpara in Europe. Cinacalcet is used to treat secondary hyperparathyroidism (elevated parathyroid hormone levels), a consequence of end-stage renal disease.".
- Cinacalcet label "Cinacalcet".
- Cinacalcet label "Cinacalcet".
- Cinacalcet label "Cinacalcet".
- Cinacalcet label "Cinacalcet".
- Cinacalcet label "Cynakalcet".
- Cinacalcet sameAs Cinacalcet.
- Cinacalcet sameAs Cinacalcet.
- Cinacalcet sameAs Cinacalcet.
- Cinacalcet sameAs Cynakalcet.
- Cinacalcet sameAs m.064_tq.
- Cinacalcet sameAs Q193978.
- Cinacalcet sameAs Q193978.
- Cinacalcet sameAs cinacalcet.
- Cinacalcet sameAs DB01012.
- Cinacalcet sameAs 156419.
- Cinacalcet wasDerivedFrom Cinacalcet?oldid=604688985.
- Cinacalcet depiction Cinacalcet_Structural_Formulae.png.
- Cinacalcet isPrimaryTopicOf Cinacalcet.