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- Ciproxifan abstract "Ciproxifan is an extremely potent histamine H3 inverse agonist/antagonist.The histamine H3 receptor is an inhibitory autoreceptor located on histaminergic nerve terminals, and is believed to be involved in modulating the release of histamine in the brain. Histamine has an excitatory effect in the brain via H1 receptors in the cerebral cortex, and so drugs such as ciproxifan which block the H3 receptor and consequently allow more histamine to be released have an alertness-promoting effect.Ciproxifan produces wakefulness and attentiveness in animal studies, and produced cognitive enhancing effects without prominent stimulant effects at relatively low levels of receptor occupancy, and pronounced wakefulness at higher doses. It has therefore been proposed as a potential treatment for sleep disorders such as narcolepsy and to improve vigilance in old age, particularly in the treatment of conditions such as Alzheimer's disease. It also potentiated the effects of antipsychotic drugs, and has been suggested as an adjuvant treatment for schizophrenia.".
- Ciproxifan atcPrefix "none".
- Ciproxifan casNumber "184025-19-2".
- Ciproxifan iupacName "(cyclopropyl 4-(3-(1H-imidazol-4-yl)propyloxy)phenyl ketone)".
- Ciproxifan pubchem "6422124".
- Ciproxifan thumbnail Ciproxifan.svg?width=300.
- Ciproxifan wikiPageID "9752277".
- Ciproxifan wikiPageRevisionID "593769809".
- Ciproxifan atcPrefix "none".
- Ciproxifan c "16".
- Ciproxifan casNumber "184025".
- Ciproxifan chembl "14638".
- Ciproxifan chemspiderid "4927646".
- Ciproxifan h "18".
- Ciproxifan hasPhotoCollection Ciproxifan.
- Ciproxifan inchi "1".
- Ciproxifan inchikey "ACQBHJXEAYTHCY-UHFFFAOYAB".
- Ciproxifan iupacName "(cyclopropyl 4-phenyl ketone)".
- Ciproxifan iupharLigand "1265".
- Ciproxifan molecularWeight "270.33".
- Ciproxifan n "2".
- Ciproxifan o "2".
- Ciproxifan pubchem "6422124".
- Ciproxifan smiles "C1CC1CC2=CC=COCCCC3=CN=CN3".
- Ciproxifan stdinchi "1".
- Ciproxifan stdinchikey "ACQBHJXEAYTHCY-UHFFFAOYSA-N".
- Ciproxifan verifiedfields "changed".
- Ciproxifan verifiedrevid "413077621".
- Ciproxifan width "200".
- Ciproxifan subject Category:Aromatic_ketones.
- Ciproxifan subject Category:Cyclopropanes.
- Ciproxifan subject Category:H3_receptor_antagonists.
- Ciproxifan subject Category:Imidazoles.
- Ciproxifan subject Category:Nootropics.
- Ciproxifan subject Category:Phenol_ethers.
- Ciproxifan type Abstraction100002137.
- Ciproxifan type AromaticKetones.
- Ciproxifan type Base114618253.
- Ciproxifan type Chemical114806838.
- Ciproxifan type Compound114818238.
- Ciproxifan type Element114840755.
- Ciproxifan type Imidazole114916670.
- Ciproxifan type Imidazoles.
- Ciproxifan type Ketone114926294.
- Ciproxifan type Material114580897.
- Ciproxifan type Matter100020827.
- Ciproxifan type OrganicCompound114727670.
- Ciproxifan type Part113809207.
- Ciproxifan type PhenolEthers.
- Ciproxifan type PhysicalEntity100001930.
- Ciproxifan type Quintessence114847103.
- Ciproxifan type Relation100031921.
- Ciproxifan type Substance100019613.
- Ciproxifan type Drug.
- Ciproxifan type DrugProduct.
- Ciproxifan type FunctionalSubstance.
- Ciproxifan comment "Ciproxifan is an extremely potent histamine H3 inverse agonist/antagonist.The histamine H3 receptor is an inhibitory autoreceptor located on histaminergic nerve terminals, and is believed to be involved in modulating the release of histamine in the brain.".
- Ciproxifan label "Ciproxifan".
- Ciproxifan label "Ciproxifan".
- Ciproxifan sameAs Ciproxifan.
- Ciproxifan sameAs m.02pr2tr.
- Ciproxifan sameAs Q5121322.
- Ciproxifan sameAs Q5121322.
- Ciproxifan sameAs Ciproxifan.
- Ciproxifan wasDerivedFrom Ciproxifan?oldid=593769809.
- Ciproxifan depiction Ciproxifan.svg.
- Ciproxifan isPrimaryTopicOf Ciproxifan.