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- Circumventricular_organs abstract "Circumventricular organs (CVOs) are structures in the brain that are characterized by their extensive vasculature and lack of a normal blood brain barrier (BBB). The CVOs allow for the linkage between the central nervous system and peripheral blood flow; additionally they are an integral part of neuroendocrine function. The lack of a blood brain barrier allows the CVOs to act as an alternative route for peptides and hormones in the neural tissue to the peripheral blood stream, while still protecting it from toxic substances. CVOs can be classified in two ways, the sensory and the secretory organs. The sensory organs include the area postrema (AP), the subfornical organ (SFO) and the organum vasculosum of lamina terminalis (OVLT). They have the ability to sense plasma molecules and then pass that information into other regions of the brain. Through this, they provide direct information to the autonomic nervous system from systemic circulation. The secretory organs include the subcommissural organ (SCO), the posterior pituitary (also known as the neurohypophysis), the pineal gland, the median eminence and the intermediate lobe of the pituitary. These organs are responsible for secreting hormones and glycoproteins into the peripheral vascular system using feedback from both the brain environment and external stimuli.All of the circumventricular organs, besides the SCO, contain extensive vasculature and fenestrated capillaries which leads to a ‘leaky’ BBB at the site of the organs. Furthermore, all CVOs contain neural tissue, allowing them to play a role in the neuroendocrine system. It is highly debated if the choroid plexus can be included as a CVO. It has a high concentration of fenestrated capillaries, but its lack of neural tissue and its primary role of producing cerebrospinal fluid (CSF) usually excludes the choroid plexus from the CVO classification.Research has also linked CVOs to body fluid regulation, cardiovascular functions, immune responses, thirst, feeding behavior and reproductive behavior.".
- Circumventricular_organs wikiPageID "4280522".
- Circumventricular_organs wikiPageRevisionID "592451292".
- Circumventricular_organs hasPhotoCollection Circumventricular_organs.
- Circumventricular_organs subject Category:Cerebrum.
- Circumventricular_organs type BodyPart105220461.
- Circumventricular_organs type Brain105481095.
- Circumventricular_organs type NeuralStructure105462674.
- Circumventricular_organs type Part109385911.
- Circumventricular_organs type PhysicalEntity100001930.
- Circumventricular_organs type Structure105225602.
- Circumventricular_organs type Thing100002452.
- Circumventricular_organs type AnatomicalStructure.
- Circumventricular_organs type Brain.
- Circumventricular_organs type AnimalBodyPart.
- Circumventricular_organs type Brain.
- Circumventricular_organs type BiologicalObject.
- Circumventricular_organs comment "Circumventricular organs (CVOs) are structures in the brain that are characterized by their extensive vasculature and lack of a normal blood brain barrier (BBB). The CVOs allow for the linkage between the central nervous system and peripheral blood flow; additionally they are an integral part of neuroendocrine function.".
- Circumventricular_organs label "Circumventriculair orgaan".
- Circumventricular_organs label "Circumventricular organs".
- Circumventricular_organs label "Narządy okołokomorowe".
- Circumventricular_organs label "Organe circumventriculaire".
- Circumventricular_organs label "Organi circumventricolari".
- Circumventricular_organs label "Zirkumventrikuläres Organ".
- Circumventricular_organs label "室周器".
- Circumventricular_organs sameAs Zirkumventrikuläres_Organ.
- Circumventricular_organs sameAs Organe_circumventriculaire.
- Circumventricular_organs sameAs Organi_circumventricolari.
- Circumventricular_organs sameAs Circumventriculair_orgaan.
- Circumventricular_organs sameAs Narządy_okołokomorowe.
- Circumventricular_organs sameAs m.0btxlc.
- Circumventricular_organs sameAs Q205925.
- Circumventricular_organs sameAs Q205925.
- Circumventricular_organs sameAs Circumventricular_organs.
- Circumventricular_organs wasDerivedFrom Circumventricular_organs?oldid=592451292.
- Circumventricular_organs isPrimaryTopicOf Circumventricular_organs.
- Circumventricular_organs name "Circumventricular organs".