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- Cystine_knot abstract "A cystine knot is a protein structural motif containing three disulfide bridges (formed from pairs of cysteine molecules). The sections of polypeptide that occur between two of them form a loop through which a third disulfide bond passes, forming a rotaxane substructure. It occurs in many proteins across many species and provides considerable structural stability. There are three types of cystine knot, which differ in the topology of the disulfide bonds: The Growth Factor Cystine Knot (GFCK) Inhibitor Cystine Knot (ICK) common in spider and snail toxins Cyclic Cystine Knot, or cyclotideThe growth factor cystine knot (GFCK) was first observed in the structure of Nerve Growth Factor, solved by X-ray crystallography and published in 1991 by Tom Blundell in Nature. All GFCK structures that have been determined are dimeric, but their dimerization modes in different classes are different.".
- Cystine_knot symbol "Cys_knot".
- Cystine_knot thumbnail PDB_1hcn_EBI.jpg?width=300.
- Cystine_knot wikiPageID "16117606".
- Cystine_knot wikiPageRevisionID "593934902".
- Cystine_knot caption "Structure of human chorionic gonadotropin.".
- Cystine_knot hasPhotoCollection Cystine_knot.
- Cystine_knot interpro "IPR006208".
- Cystine_knot name "Cystine-knot domain".
- Cystine_knot pdb ", , , ,".
- Cystine_knot pfam "PF00007".
- Cystine_knot pfamClan "CL0079".
- Cystine_knot scop "1".
- Cystine_knot symbol "Cys_knot".
- Cystine_knot subject Category:Protein_structure.
- Cystine_knot type Biomolecule.
- Cystine_knot type Protein.
- Cystine_knot type BiologicalObject.
- Cystine_knot comment "A cystine knot is a protein structural motif containing three disulfide bridges (formed from pairs of cysteine molecules). The sections of polypeptide that occur between two of them form a loop through which a third disulfide bond passes, forming a rotaxane substructure. It occurs in many proteins across many species and provides considerable structural stability.".
- Cystine_knot label "Cystine knot".
- Cystine_knot label "Pont cystine".
- Cystine_knot label "Ponte cistina".
- Cystine_knot sameAs Pont_cystine.
- Cystine_knot sameAs Ponte_cistina.
- Cystine_knot sameAs m.03w9rnk.
- Cystine_knot sameAs Q9305217.
- Cystine_knot sameAs Q9305217.
- Cystine_knot wasDerivedFrom Cystine_knot?oldid=593934902.
- Cystine_knot depiction PDB_1hcn_EBI.jpg.
- Cystine_knot isPrimaryTopicOf Cystine_knot.