Matches in DBpedia 2014 for { <http://dbpedia.org/resource/DUSP2> ?p ?o. }
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- DUSP2 abstract "Dual specificity protein phosphatase 2 is an enzyme that in humans is encoded by the DUSP2 gene.The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK1 and ERK2, is predominantly expressed in hematopoietic tissues, and is localized in the nucleus.".
- DUSP2 entrezgene "1844".
- DUSP2 wikiPageID "15030425".
- DUSP2 wikiPageRevisionID "591118877".
- DUSP2 hasPhotoCollection DUSP2.
- DUSP2 requireManualInspection "no".
- DUSP2 summaryText "The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein kinase superfamily , which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK1 and ERK2, is predominantly expressed in hematopoietic tissues, and is localized in the nucleus.".
- DUSP2 updateCitations "yes".
- DUSP2 updatePage "yes".
- DUSP2 updateProteinBox "yes".
- DUSP2 updateSummary "yes".
- DUSP2 type Biomolecule.
- DUSP2 type Protein.
- DUSP2 type BiologicalObject.
- DUSP2 comment "Dual specificity protein phosphatase 2 is an enzyme that in humans is encoded by the DUSP2 gene.The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues.".
- DUSP2 label "DUSP2".
- DUSP2 sameAs m.03h55z9.
- DUSP2 sameAs Q5206314.
- DUSP2 sameAs Q5206314.
- DUSP2 wasDerivedFrom DUSP2?oldid=591118877.
- DUSP2 isPrimaryTopicOf DUSP2.