Matches in DBpedia 2014 for { <http://dbpedia.org/resource/DUSP5> ?p ?o. }
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- DUSP5 abstract "Dual specificity protein phosphatase 5 is an enzyme that in humans is encoded by the DUSP5 gene.The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK1/2, is expressed in a variety of tissues with the highest levels in pancreas and brain, and is localized in the nucleus.".
- DUSP5 entrezgene "1847".
- DUSP5 wikiPageID "15213515".
- DUSP5 wikiPageRevisionID "591118993".
- DUSP5 hasPhotoCollection DUSP5.
- DUSP5 requireManualInspection "no".
- DUSP5 summaryText "The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein kinase superfamily , which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK1/2, is expressed in a variety of tissues with the highest levels in pancreas and brain, and is localized in the nucleus.".
- DUSP5 updateCitations "yes".
- DUSP5 updatePage "yes".
- DUSP5 updateProteinBox "yes".
- DUSP5 updateSummary "yes".
- DUSP5 type Biomolecule.
- DUSP5 type Protein.
- DUSP5 type BiologicalObject.
- DUSP5 comment "Dual specificity protein phosphatase 5 is an enzyme that in humans is encoded by the DUSP5 gene.The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues.".
- DUSP5 label "DUSP5".
- DUSP5 sameAs m.03hm1fp.
- DUSP5 sameAs Q5206320.
- DUSP5 sameAs Q5206320.
- DUSP5 wasDerivedFrom DUSP5?oldid=591118993.
- DUSP5 isPrimaryTopicOf DUSP5.