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- Delamanid abstract "Delamanid (USAN, codenamed OPC-67683) is an experimental drug for the treatment of multi-drug-resistant tuberculosis. It works by blocking the synthesis of mycolic acids in Mycobacterium tuberculosis, the organism which causes tuberculosis, thus destabilising its cell wall.In phase II clinical trials, the drug was used in combination with standard treatments, such as four or five of the drugs ethambutol, isoniazid, pyrazinamide, rifampicin, aminoglycoside antibiotics, and quinolones. Healing rates (measured as sputum culture conversion) were significantly better in patients who additionally took delamanid.The European Medicines Agency (EMA) recommended conditional marketing authorization for delamanid in adults with multidrug-resistant pulmonary tuberculosis without other treatment options because of resistance or tolerability. The EMA considered the data show that the benefits of delamanid outweigh the risks, but that additional studies were needed on the long-term effectiveness.".
- Delamanid atcPrefix "J04".
- Delamanid atcSuffix "AK06".
- Delamanid casNumber "681492-22-8".
- Delamanid iupacName "(2R)-2-Methyl-6-nitro-2-[(4-{4-[4-(trifluoromethoxy)phenoxy]-1-piperidinyl}phenoxy)methyl]-2,3-dihydroimidazo[2,1-b][1,3]oxazole".
- Delamanid pubchem "6480466".
- Delamanid thumbnail Delamanid.svg?width=300.
- Delamanid wikiPageID "38887135".
- Delamanid wikiPageRevisionID "601183552".
- Delamanid atcPrefix "J04".
- Delamanid atcSuffix "AK06".
- Delamanid c "25".
- Delamanid casNumber "681492".
- Delamanid chembl "218650".
- Delamanid chemspiderid "4981055".
- Delamanid f "3".
- Delamanid h "25".
- Delamanid hasPhotoCollection Delamanid.
- Delamanid iupacName "-2".
- Delamanid legalStatus "Investigational".
- Delamanid molecularWeight "534.48".
- Delamanid n "4".
- Delamanid o "6".
- Delamanid pubchem "6480466".
- Delamanid smiles "FCOc5ccccc5".
- Delamanid stdinchi "1".
- Delamanid stdinchikey "XDAOLTSRNUSPPH-XMMPIXPASA-N".
- Delamanid synonyms "OPC-67683".
- Delamanid subject Category:Tuberculosis.
- Delamanid type Drug.
- Delamanid type FunctionalSubstance.
- Delamanid comment "Delamanid (USAN, codenamed OPC-67683) is an experimental drug for the treatment of multi-drug-resistant tuberculosis. It works by blocking the synthesis of mycolic acids in Mycobacterium tuberculosis, the organism which causes tuberculosis, thus destabilising its cell wall.In phase II clinical trials, the drug was used in combination with standard treatments, such as four or five of the drugs ethambutol, isoniazid, pyrazinamide, rifampicin, aminoglycoside antibiotics, and quinolones.".
- Delamanid label "Delamanid".
- Delamanid sameAs m.0ryvsfv.
- Delamanid sameAs Q15408413.
- Delamanid sameAs Q15408413.
- Delamanid wasDerivedFrom Delamanid?oldid=601183552.
- Delamanid depiction Delamanid.svg.
- Delamanid isPrimaryTopicOf Delamanid.