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- Desipramine abstract "Desipramine (also known as desmethylimipramine) is a tricyclic antidepressant (TCA). It inhibits the reuptake of norepinephrine and to a minor extent serotonin. It is used to treat depression, but not considered a first line treatment since the introduction of SSRI antidepressants. Desipramine is an active metabolite of imipramine. It is sold under the brand names Treyzafagit, Norpramin and Pertofrane.Along with other tricyclics, desipramine has found use in treating neuropathic pain. The mechanism of action seems to involve the activation, through norepinephrine reuptake inhibition, of descending pathways in the spinal cord that block pain signals from ascending to the brain. Desipramine is one of the most potent and selectivemedications in this respect. It may also be used to treat symptoms of Attention Deficit Hyperactivity Disorder, as the underproduction of norepinephrine has been increasingly linked to symptoms associated with Attention Deficit Disorder[citation needed]. It may also be used to treat symptoms of cocaine withdrawal.[citation needed]".
- Desipramine atcPrefix "N06".
- Desipramine atcSuffix "AA01".
- Desipramine bioavailability "73.0".
- Desipramine casNumber "50-47-5".
- Desipramine chEBI "47781".
- Desipramine drugbank "DB01151".
- Desipramine fdaUniiCode "TG537D343B".
- Desipramine iupacName "3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N-methylpropan-1-amine".
- Desipramine pubchem "2995".
- Desipramine thumbnail Desipramine.svg?width=300.
- Desipramine wikiPageExternalLink article.htm.
- Desipramine wikiPageExternalLink 713305?sssdmh=dm1.563907&src=ddd&uac=122237BK.
- Desipramine wikiPageExternalLink p30-n03.html.
- Desipramine wikiPageExternalLink a682387.html.
- Desipramine wikiPageID "1515417".
- Desipramine wikiPageRevisionID "601588980".
- Desipramine atcPrefix "N06".
- Desipramine atcSuffix "AA01".
- Desipramine bioavailability "73".
- Desipramine c "18".
- Desipramine casNumber "50".
- Desipramine chebi "47781".
- Desipramine chembl "72".
- Desipramine chemspiderid "2888".
- Desipramine drugbank "DB01151".
- Desipramine eliminationHalfLife "-86400.0".
- Desipramine excretion "Urine".
- Desipramine h "22".
- Desipramine hasPhotoCollection Desipramine.
- Desipramine inchi "1".
- Desipramine inchikey "HCYAFALTSJYZDH-UHFFFAOYAV".
- Desipramine iupacName "3".
- Desipramine iupharLigand "2399".
- Desipramine kegg "D07791".
- Desipramine legalUs "Rx-only".
- Desipramine medlineplus "a682387".
- Desipramine metabolism "Hepatic".
- Desipramine molecularWeight "266.381".
- Desipramine n "2".
- Desipramine pregnancyUs "C".
- Desipramine pubchem "2995".
- Desipramine routesOfAdministration "Oral".
- Desipramine smiles "c1cc3cCCc2cN3CCCNC".
- Desipramine stdinchi "1".
- Desipramine stdinchikey "HCYAFALTSJYZDH-UHFFFAOYSA-N".
- Desipramine tradename "Norpramin".
- Desipramine unii "TG537D343B".
- Desipramine verifiedrevid "477166380".
- Desipramine subject Category:Dibenzazepines.
- Desipramine subject Category:Tricyclic_antidepressants.
- Desipramine type Drug.
- Desipramine type DrugProduct.
- Desipramine type FunctionalSubstance.
- Desipramine comment "Desipramine (also known as desmethylimipramine) is a tricyclic antidepressant (TCA). It inhibits the reuptake of norepinephrine and to a minor extent serotonin. It is used to treat depression, but not considered a first line treatment since the introduction of SSRI antidepressants. Desipramine is an active metabolite of imipramine. It is sold under the brand names Treyzafagit, Norpramin and Pertofrane.Along with other tricyclics, desipramine has found use in treating neuropathic pain.".
- Desipramine label "Desipramin".
- Desipramine label "Desipramina".
- Desipramine label "Desipramine".
- Desipramine label "Dezypramina".
- Desipramine label "Désipramine".
- Desipramine label "Дезипрамин".
- Desipramine sameAs Desipramin.
- Desipramine sameAs Désipramine.
- Desipramine sameAs Dezypramina.
- Desipramine sameAs Desipramina.
- Desipramine sameAs m.0577dm.
- Desipramine sameAs Q423288.
- Desipramine sameAs Q423288.
- Desipramine sameAs desipramine.
- Desipramine sameAs DB01151.
- Desipramine sameAs 2995.
- Desipramine wasDerivedFrom Desipramine?oldid=601588980.
- Desipramine depiction Desipramine.svg.
- Desipramine isPrimaryTopicOf Desipramine.