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- Development_of_analogs_of_thalidomide abstract "The development of analogs of thalidomide was precipitated by the discovery of the anti-angiogenic and anti-inflammatory properties of the drug yielding a new way of fighting cancer as well as some inflammatory diseases after it had been banned in 1961. The problems with thalidomide included; teratogenic side effects, high incidence of other adverse reactions, poor solubility in water and poor absorption from the intestines. In 1998 thalidomide was approved by the US Food and Drug Administration (FDA) for use in newly diagnosed multiple myeloma (MM) under strict regulations. This has led to the development of a number of analogs with fewer side effects and increased potency which include; lenalidomide, (currently marketed), pomalidomide and apremilast (currently in clinical trials), all of which are manufactured by Celgene.".
- Development_of_analogs_of_thalidomide thumbnail Thalidomide-2D-skeletal-wavy.svg?width=300.
- Development_of_analogs_of_thalidomide wikiPageID "37125103".
- Development_of_analogs_of_thalidomide wikiPageRevisionID "605533043".
- Development_of_analogs_of_thalidomide alt "Thalidomide".
- Development_of_analogs_of_thalidomide atcPrefix "L04AX".
- Development_of_analogs_of_thalidomide biologicalTarget Immunosuppression.
- Development_of_analogs_of_thalidomide caption "Thalidomide, the parent drug of thalidomide analogs.".
- Development_of_analogs_of_thalidomide name "Thalidomide".
- Development_of_analogs_of_thalidomide subject Category:Clinical_research.
- Development_of_analogs_of_thalidomide subject Category:Drug_discovery.
- Development_of_analogs_of_thalidomide subject Category:Immunosuppressants.
- Development_of_analogs_of_thalidomide subject Category:Medicinal_chemistry.
- Development_of_analogs_of_thalidomide subject Category:Orphan_drugs.
- Development_of_analogs_of_thalidomide subject Category:PDE4_inhibitors.
- Development_of_analogs_of_thalidomide subject Category:Pharmacology.
- Development_of_analogs_of_thalidomide subject Category:TNF_inhibitors.
- Development_of_analogs_of_thalidomide subject Category:Teratogens.
- Development_of_analogs_of_thalidomide comment "The development of analogs of thalidomide was precipitated by the discovery of the anti-angiogenic and anti-inflammatory properties of the drug yielding a new way of fighting cancer as well as some inflammatory diseases after it had been banned in 1961. The problems with thalidomide included; teratogenic side effects, high incidence of other adverse reactions, poor solubility in water and poor absorption from the intestines.".
- Development_of_analogs_of_thalidomide label "Development of analogs of thalidomide".
- Development_of_analogs_of_thalidomide sameAs m.0n40s33.
- Development_of_analogs_of_thalidomide sameAs Q5282007.
- Development_of_analogs_of_thalidomide sameAs Q5282007.
- Development_of_analogs_of_thalidomide wasDerivedFrom Development_of_analogs_of_thalidomide?oldid=605533043.
- Development_of_analogs_of_thalidomide depiction Thalidomide-2D-skeletal-wavy.svg.
- Development_of_analogs_of_thalidomide isPrimaryTopicOf Development_of_analogs_of_thalidomide.