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- Discovery_and_development_of_mTOR_inhibitors abstract "Mammalian target of rapamycin (mTOR) is a serine/threonine kinase, which belongs to phosphatidylinositol-3 kinase (PI3K) related kinases (PIKKs) family. It regulates cellular metabolism, growth, and proliferation, and therefore is a target for the development of a number of mTOR inhibitors.It effects downstream pathway and forms two complexes, mTORC1 and mTORC2. The most established mTOR inhibitors are so-called rapalogs (rapamycin and its analogs), which have shown tumor responses in clinical trials against various tumor types.".
- Discovery_and_development_of_mTOR_inhibitors thumbnail Sirolimus3d.png?width=300.
- Discovery_and_development_of_mTOR_inhibitors wikiPageID "37125686".
- Discovery_and_development_of_mTOR_inhibitors wikiPageRevisionID "590959631".
- Discovery_and_development_of_mTOR_inhibitors hasPhotoCollection Discovery_and_development_of_mTOR_inhibitors.
- Discovery_and_development_of_mTOR_inhibitors subject Category:Antineoplastic_drugs.
- Discovery_and_development_of_mTOR_inhibitors subject Category:Cancer_treatments.
- Discovery_and_development_of_mTOR_inhibitors subject Category:Drug_discovery.
- Discovery_and_development_of_mTOR_inhibitors subject Category:Human_proteins.
- Discovery_and_development_of_mTOR_inhibitors subject Category:Oncology.
- Discovery_and_development_of_mTOR_inhibitors subject Category:Pharmacology.
- Discovery_and_development_of_mTOR_inhibitors subject Category:Signal_transduction.
- Discovery_and_development_of_mTOR_inhibitors subject Category:Tor_signaling_pathway.
- Discovery_and_development_of_mTOR_inhibitors comment "Mammalian target of rapamycin (mTOR) is a serine/threonine kinase, which belongs to phosphatidylinositol-3 kinase (PI3K) related kinases (PIKKs) family. It regulates cellular metabolism, growth, and proliferation, and therefore is a target for the development of a number of mTOR inhibitors.It effects downstream pathway and forms two complexes, mTORC1 and mTORC2.".
- Discovery_and_development_of_mTOR_inhibitors label "Discovery and development of mTOR inhibitors".
- Discovery_and_development_of_mTOR_inhibitors sameAs m.0n3szjy.
- Discovery_and_development_of_mTOR_inhibitors sameAs Q5282002.
- Discovery_and_development_of_mTOR_inhibitors sameAs Q5282002.
- Discovery_and_development_of_mTOR_inhibitors wasDerivedFrom Discovery_and_development_of_mTOR_inhibitors?oldid=590959631.
- Discovery_and_development_of_mTOR_inhibitors depiction Sirolimus3d.png.
- Discovery_and_development_of_mTOR_inhibitors isPrimaryTopicOf Discovery_and_development_of_mTOR_inhibitors.