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- Dronedarone abstract "Dronedarone (development codename SR33589 and marketed as Multaq) is a drug by Sanofi-Aventis, mainly for the indication of cardiac arrhythmias. It was approved by the FDA on July 2, 2009. It was recommended as an alternative to amiodarone for the treatment of atrial fibrillation and atrial flutter in people whose hearts have either returned to normal rhythm or who undergo drug therapy or electric shock treatment i.e. direct current cardioversion (DCCV) to maintain normal rhythm. In the United States, the FDA approved label includes a claim for reducing hospitalization, but not for reducing mortality, as a reduction in mortality was not demonstrated in the clinical development program. A trial of the drug in heart failure was stopped as an interim analysis showed a possible increase in heart failure deaths, in patients with moderate to severe CHF.The U.S. label for dronedarone includes a black box warning, stating that dronedarone is contraindicated in patients with NYHA Class IV heart failure, with NYHA Class II–III heart failure with a recent decompensation requiring hospitalization or referral to a specialized heart failure clinic, or with permanent atrial fibrillation." Dronedarone is also associated with rare case of severe liver damage, including liver failure.".
- Dronedarone atcPrefix "C01".
- Dronedarone atcSuffix "BD07".
- Dronedarone bioavailability "15.0".
- Dronedarone casNumber "141626-36-0".
- Dronedarone chEBI "50659".
- Dronedarone fdaUniiCode "JQZ1L091Y2".
- Dronedarone iupacName "N-(2-Butyl-3-(p-(3-(dibutylamino)propoxy)benzoyl)-5-benzofuranyl)methanesulfonamide".
- Dronedarone pubchem "208898".
- Dronedarone thumbnail Dronedarone_structure.svg?width=300.
- Dronedarone wikiPageID "7778362".
- Dronedarone wikiPageRevisionID "598228263".
- Dronedarone atcPrefix "1.0".
- Dronedarone atcSuffix "BD07".
- Dronedarone bioavailability "15.0".
- Dronedarone c "31".
- Dronedarone casNumber "141626".
- Dronedarone chebi "50659".
- Dronedarone chembl "184412".
- Dronedarone chemspiderid "180996".
- Dronedarone eliminationHalfLife "68400.0".
- Dronedarone excretion "Feces , urine".
- Dronedarone h "44".
- Dronedarone hasPhotoCollection Dronedarone.
- Dronedarone inchi "1".
- Dronedarone inchikey "ZQTNQVWKHCQYLQ-UHFFFAOYAL".
- Dronedarone iupacName "N-methanesulfonamide".
- Dronedarone kegg "D02537".
- Dronedarone legalUs "Rx-only".
- Dronedarone licenceUs "Dronedarone".
- Dronedarone medlineplus "a609034".
- Dronedarone metabolism "Extensive hepatic".
- Dronedarone molecularWeight "556.758".
- Dronedarone n "2".
- Dronedarone o "5".
- Dronedarone pregnancyUs "X".
- Dronedarone proteinBound ">98%".
- Dronedarone pubchem "208898".
- Dronedarone routesOfAdministration "Oral".
- Dronedarone s "1".
- Dronedarone smiles "O=SC".
- Dronedarone stdinchi "1".
- Dronedarone stdinchikey "ZQTNQVWKHCQYLQ-UHFFFAOYSA-N".
- Dronedarone tradename "Multaq".
- Dronedarone unii "JQZ1L091Y2".
- Dronedarone verifiedfields "changed".
- Dronedarone verifiedrevid "461091509".
- Dronedarone watchedfields "changed".
- Dronedarone subject Category:Antiarrhythmic_agents.
- Dronedarone subject Category:Aromatic_ketones.
- Dronedarone subject Category:Benzofurans.
- Dronedarone subject Category:Phenol_ethers.
- Dronedarone subject Category:Sulfonamides.
- Dronedarone type Abstraction100002137.
- Dronedarone type AromaticKetones.
- Dronedarone type Benzofuran114898101.
- Dronedarone type Benzofurans.
- Dronedarone type Chemical114806838.
- Dronedarone type Compound114818238.
- Dronedarone type Element114840755.
- Dronedarone type Ketone114926294.
- Dronedarone type Material114580897.
- Dronedarone type Matter100020827.
- Dronedarone type OrganicCompound114727670.
- Dronedarone type Part113809207.
- Dronedarone type PhenolEthers.
- Dronedarone type PhysicalEntity100001930.
- Dronedarone type Quintessence114847103.
- Dronedarone type Relation100031921.
- Dronedarone type Substance100019613.
- Dronedarone type Drug.
- Dronedarone type DrugProduct.
- Dronedarone type FunctionalSubstance.
- Dronedarone comment "Dronedarone (development codename SR33589 and marketed as Multaq) is a drug by Sanofi-Aventis, mainly for the indication of cardiac arrhythmias. It was approved by the FDA on July 2, 2009. It was recommended as an alternative to amiodarone for the treatment of atrial fibrillation and atrial flutter in people whose hearts have either returned to normal rhythm or who undergo drug therapy or electric shock treatment i.e. direct current cardioversion (DCCV) to maintain normal rhythm.".
- Dronedarone label "Dronedaron".
- Dronedarone label "Dronedarona".
- Dronedarone label "Dronedarone".
- Dronedarone label "Dronedarone".
- Dronedarone label "Dronédarone".
- Dronedarone sameAs Dronedaron.
- Dronedarone sameAs Dronedarona.
- Dronedarone sameAs Dronédarone.
- Dronedarone sameAs Dronedarone.
- Dronedarone sameAs m.01xm8sc.
- Dronedarone sameAs Q408637.
- Dronedarone sameAs Q408637.
- Dronedarone sameAs Dronedarone.
- Dronedarone wasDerivedFrom Dronedarone?oldid=598228263.
- Dronedarone depiction Dronedarone_structure.svg.
- Dronedarone isPrimaryTopicOf Dronedarone.