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- EC50 abstract "The term half maximal effective concentration (EC50) refers to the concentration of a drug, antibody or toxicant which induces a response halfway between the baseline and maximum after a specified exposure time. It is commonly used as a measure of drug's potency.The EC50 of a graded dose response curve therefore represents the concentration of a compound where 50% of its maximal effect is observed. The EC50 of a quantal dose response curve represents the concentration of a compound where 50% of the population exhibit a response, after a specified exposure duration.It is also related to IC50 which is a measure of a compound's inhibition (50% inhibition). For competition binding assays and functional antagonist assays IC50 is the most common summary measure of the dose-response curve. For agonist/stimulator assays the most common summary measure is the EC50.A small changes in ligand concentration typically result in rapid changes in response in the biological system, following a sigmoidal function.The inflection point at which the increase in response with increasing ligand concentration begins to slow is the EC50. Which can be mathematically determined by derivation of the best-fit line. While relying on a graph for estimation is more convenient, this typical method yields less accurate results and less precise.".
- EC50 wikiPageExternalLink 597.
- EC50 wikiPageExternalLink ec50.html.
- EC50 wikiPageExternalLink IC50.htm.
- EC50 wikiPageID "3742950".
- EC50 wikiPageRevisionID "590198164".
- EC50 hasPhotoCollection EC50.
- EC50 subject Category:Pharmacology.
- EC50 subject Category:Toxicology.
- EC50 comment "The term half maximal effective concentration (EC50) refers to the concentration of a drug, antibody or toxicant which induces a response halfway between the baseline and maximum after a specified exposure time. It is commonly used as a measure of drug's potency.The EC50 of a graded dose response curve therefore represents the concentration of a compound where 50% of its maximal effect is observed.".
- EC50 label "Concentration efficace médiane".
- EC50 label "EC50".
- EC50 label "EC50".
- EC50 label "EC50".
- EC50 label "EC50".
- EC50 label "EC50".
- EC50 sameAs EC50.
- EC50 sameAs Concentration_efficace_médiane.
- EC50 sameAs EC50.
- EC50 sameAs EC50.
- EC50 sameAs m.09yld5.
- EC50 sameAs Q286136.
- EC50 sameAs Q286136.
- EC50 wasDerivedFrom EC50?oldid=590198164.
- EC50 isPrimaryTopicOf EC50.