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- Ecallantide abstract "Ecallantide (trade name Kalbitor, investigational name DX-88) is a drug used for the treatment of hereditary angioedema (HAE) and in the prevention of blood loss in cardiothoracic surgery. It is an inhibitor of the protein kallikrein and a 60-amino acid polypeptide which was developed from a Kunitz domain through phage display to mimic antibodies inhibiting kallikrein. On November 27, 2009, ecallantide was approved by the U.S. Food and Drug Administration for the treatment of acute attacks of hereditary angioedema for persons over 16 years of age.If approved for cardiothoracic surgery, it could become a replacement for aprotinin,[citation needed] which was withdrawn in 2007 after being shown to cause complications.".
- Ecallantide atcPrefix "B06".
- Ecallantide atcSuffix "AC03".
- Ecallantide casNumber "460738-38-9".
- Ecallantide fdaUniiCode "5Q6TZN2HNM".
- Ecallantide iupacName "[Glu20,Ala21,Arg36,Ala38,His39,Pro40,Trp42]tissue factor pathway inhibitor (human)-(20-79)-peptide (modified on reactive bond region Kunitz inhibitor 1 domain containing fragment)".
- Ecallantide pubchem "44152182".
- Ecallantide wikiPageID "18617275".
- Ecallantide wikiPageRevisionID "591136440".
- Ecallantide atcPrefix "B06".
- Ecallantide atcSuffix "AC03".
- Ecallantide c "305".
- Ecallantide casNumber "460738".
- Ecallantide chembl "1201837".
- Ecallantide chemspiderid "NA".
- Ecallantide eliminationHalfLife "9000.0".
- Ecallantide excretion Kidney.
- Ecallantide h "442".
- Ecallantide hasPhotoCollection Ecallantide.
- Ecallantide iupacName "[Glu20,Ala21,Arg36,Ala38,His39,Pro40,Trp42]tissue factor pathway inhibitor --peptide".
- Ecallantide legalUs "Rx-only".
- Ecallantide licenceUs "ECALLANTIDE".
- Ecallantide molecularWeight "7053.83".
- Ecallantide n "88".
- Ecallantide o "91".
- Ecallantide pregnancyUs "C".
- Ecallantide pubchem "44152182".
- Ecallantide routesOfAdministration Subcutaneous_injection.
- Ecallantide s "8".
- Ecallantide tradename "Kalbitor".
- Ecallantide unii "5".
- Ecallantide verifiedfields "changed".
- Ecallantide verifiedrevid "414410253".
- Ecallantide watchedfields "changed".
- Ecallantide subject Category:Antibody_mimetics.
- Ecallantide subject Category:Hydrolase_inhibitors.
- Ecallantide type Abstraction100002137.
- Ecallantide type Amide114724264.
- Ecallantide type Chemical114806838.
- Ecallantide type Compound114818238.
- Ecallantide type Material114580897.
- Ecallantide type Matter100020827.
- Ecallantide type OrganicCompound114727670.
- Ecallantide type Part113809207.
- Ecallantide type Peptide114743046.
- Ecallantide type Peptides.
- Ecallantide type PhysicalEntity100001930.
- Ecallantide type Relation100031921.
- Ecallantide type Substance100019613.
- Ecallantide type Drug.
- Ecallantide type DrugProduct.
- Ecallantide type FunctionalSubstance.
- Ecallantide comment "Ecallantide (trade name Kalbitor, investigational name DX-88) is a drug used for the treatment of hereditary angioedema (HAE) and in the prevention of blood loss in cardiothoracic surgery. It is an inhibitor of the protein kallikrein and a 60-amino acid polypeptide which was developed from a Kunitz domain through phage display to mimic antibodies inhibiting kallikrein. On November 27, 2009, ecallantide was approved by the U.S.".
- Ecallantide label "Ecallantid".
- Ecallantide label "Ecallantide".
- Ecallantide sameAs Ecallantid.
- Ecallantide sameAs m.04gkvm3.
- Ecallantide sameAs Q1280166.
- Ecallantide sameAs Q1280166.
- Ecallantide sameAs Ecallantide.
- Ecallantide wasDerivedFrom Ecallantide?oldid=591136440.
- Ecallantide isPrimaryTopicOf Ecallantide.