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- Ecdysteroid-phosphate_phosphatase abstract "Ecdysteroid-phosphate Phosphatase is the first structure of a steroid phosphate phosphotase containing alpha beta folds common to members of the two histidine (2H)-Phosphatase superfamily with strong homology to the Suppressor of T-cell receptor signaling-1 (Sts-1 PGM) protein. The putative EPPase PGM active site contains signature residues shared by 2H-phosphatase enzymes, including a conserved histidine (His80) that acts as a nucleophile during catalysis. The physiological substrate ecdysone 22-phosphate was modeled in a hydrophobic cavity close to the phosphate-binding site. EPPase PGM shows limited substrate specificity with an ability to hydrolyze steroid phosphates, the phospho-tyrosine (pTyr) substrate analogue para-nitrophenylphosphate ( pNPP) and pTyr-containing peptides and proteins. It has been shown that new protein tyrosine phosphatase (PTP) activity for EPPase. Also, EPPase and its closest homologues can be grouped into a distinct subfamily in the large 2H-Phosphatase superfamily of proteins.".
- Ecdysteroid-phosphate_phosphatase thumbnail EcdysonePhosphatePhosphatase.jpg?width=300.
- Ecdysteroid-phosphate_phosphatase wikiPageExternalLink mmdbsrv.cgi?uid=70358.
- Ecdysteroid-phosphate_phosphatase wikiPageExternalLink remediatedSequence.do?structureId=3C7T.
- Ecdysteroid-phosphate_phosphatase wikiPageID "29824046".
- Ecdysteroid-phosphate_phosphatase wikiPageRevisionID "433955734".
- Ecdysteroid-phosphate_phosphatase hasPhotoCollection Ecdysteroid-phosphate_phosphatase.
- Ecdysteroid-phosphate_phosphatase subject Category:EC_3.1.3.
- Ecdysteroid-phosphate_phosphatase subject Category:Hydrolases.
- Ecdysteroid-phosphate_phosphatase subject Category:Metabolic_pathways.
- Ecdysteroid-phosphate_phosphatase subject Category:Posttranslational_modification.
- Ecdysteroid-phosphate_phosphatase subject Category:Steroids.
- Ecdysteroid-phosphate_phosphatase type Abstraction100002137.
- Ecdysteroid-phosphate_phosphatase type Chemical114806838.
- Ecdysteroid-phosphate_phosphatase type Compound114818238.
- Ecdysteroid-phosphate_phosphatase type Material114580897.
- Ecdysteroid-phosphate_phosphatase type Matter100020827.
- Ecdysteroid-phosphate_phosphatase type OrganicCompound114727670.
- Ecdysteroid-phosphate_phosphatase type Part113809207.
- Ecdysteroid-phosphate_phosphatase type PhysicalEntity100001930.
- Ecdysteroid-phosphate_phosphatase type Relation100031921.
- Ecdysteroid-phosphate_phosphatase type Steroid115057744.
- Ecdysteroid-phosphate_phosphatase type Steroids.
- Ecdysteroid-phosphate_phosphatase type Substance100019613.
- Ecdysteroid-phosphate_phosphatase comment "Ecdysteroid-phosphate Phosphatase is the first structure of a steroid phosphate phosphotase containing alpha beta folds common to members of the two histidine (2H)-Phosphatase superfamily with strong homology to the Suppressor of T-cell receptor signaling-1 (Sts-1 PGM) protein. The putative EPPase PGM active site contains signature residues shared by 2H-phosphatase enzymes, including a conserved histidine (His80) that acts as a nucleophile during catalysis.".
- Ecdysteroid-phosphate_phosphatase label "Ecdysteroid-phosphate phosphatase".
- Ecdysteroid-phosphate_phosphatase sameAs m.0fq15y_.
- Ecdysteroid-phosphate_phosphatase sameAs Q5332336.
- Ecdysteroid-phosphate_phosphatase sameAs Q5332336.
- Ecdysteroid-phosphate_phosphatase sameAs Ecdysteroid-phosphate_phosphatase.
- Ecdysteroid-phosphate_phosphatase wasDerivedFrom Ecdysteroid-phosphate_phosphatase?oldid=433955734.
- Ecdysteroid-phosphate_phosphatase depiction EcdysonePhosphatePhosphatase.jpg.
- Ecdysteroid-phosphate_phosphatase isPrimaryTopicOf Ecdysteroid-phosphate_phosphatase.