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- Eledoisin abstract "Eledoisin is an undecapeptide of mollusk origin, belonging to the tachykinin family of neuropeptides.It was first isolated from the posterior salivary glands of two mollusk species Eledone muschata and Eledone aldovandi, which belong to the octopod order of Cephalopoda. Other tachykinins from nonmammalian sources include kassinin and physalaemin. The mammalian tachykinins substance P, NKA, and NKB have similar effects as tachykinins of nonmammals and have been more widely studied and characterized. These peptides exhibit a wide and complex spectrum of pharmacological and physiological activities such as vasodilation, hypertension, and stimulation of extravascular smooth muscle.Eledoisin has the amino acid sequence pGlu-Pro-Ser-Lys-Asp-Ala-Phe-Ile-Gly-Leu-Met-NH. Like all tachykinin peptides, Eledoisin shares the same consensus C-terminal sequence, that is, Phe-Xxx-Gly-Leu-Met-NH. The invariant "Phe7" residue is probably required for receptor binding. "Xxx" is either an aromatic (phenylalanine, tyrosine) or a branched aliphatic (valine, isoleucine) side chain and is thought to be important in receptor selectivity. This common region, often referred to as the "message domain," is believed to be responsible for activating the receptor. The divergent N-terminal region or the "address domain" varies in amino-acid sequence and length and is believed to play a role in determining the receptor subtype specificity.".
- Eledoisin fdaUniiCode "OKY3285J18".
- Eledoisin iupacName "(3S)-3-(2S)-6-amino-2-[[(2S)-3-hydroxy-2-[[(2S)-1-[(2S)-5-oxopyrrolidine-2-carbonyl]pyrrolidine-2-carbonyl]amino]propanoyl]amino]hexanoyl]amino]-4-[[(2S)-1-[[(2S)-1-[[(2S,3S)-1-[[2-[[(2S)-1-[[(2S)-1-amino-4-methylsulfanyl-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-3-methyl-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-1-oxopropan-2-yl]amino]-4-oxobutanoic acid".
- Eledoisin thumbnail Eledoisin_skeletal.svg?width=300.
- Eledoisin wikiPageID "14577528".
- Eledoisin wikiPageRevisionID "445020142".
- Eledoisin hasPhotoCollection Eledoisin.
- Eledoisin imagefile "Eledoisin skeletal.svg".
- Eledoisin imagefile "PDB 1mxq EBI.jpg".
- Eledoisin iupacname "-3".
- Eledoisin unii "OKY3285J18".
- Eledoisin subject Category:Invertebrate_toxins.
- Eledoisin subject Category:Neuropeptides.
- Eledoisin subject Category:Neurotransmitters.
- Eledoisin type Abstraction100002137.
- Eledoisin type Chemical114806838.
- Eledoisin type Compound114818238.
- Eledoisin type Material114580897.
- Eledoisin type Matter100020827.
- Eledoisin type Neurochemical114807410.
- Eledoisin type Neurotransmitter114807558.
- Eledoisin type Neurotransmitters.
- Eledoisin type OrganicCompound114727670.
- Eledoisin type Part113809207.
- Eledoisin type PhysicalEntity100001930.
- Eledoisin type Relation100031921.
- Eledoisin type Substance100019613.
- Eledoisin type ChemicalCompound.
- Eledoisin type ChemicalSubstance.
- Eledoisin type ChemicalSubstanceType.
- Eledoisin type ChemicalObject.
- Eledoisin type Thing.
- Eledoisin comment "Eledoisin is an undecapeptide of mollusk origin, belonging to the tachykinin family of neuropeptides.It was first isolated from the posterior salivary glands of two mollusk species Eledone muschata and Eledone aldovandi, which belong to the octopod order of Cephalopoda. Other tachykinins from nonmammalian sources include kassinin and physalaemin.".
- Eledoisin label "Eledoisin".
- Eledoisin sameAs m.03d8g5p.
- Eledoisin sameAs Q5358600.
- Eledoisin sameAs Q5358600.
- Eledoisin sameAs Eledoisin.
- Eledoisin wasDerivedFrom Eledoisin?oldid=445020142.
- Eledoisin depiction Eledoisin_skeletal.svg.
- Eledoisin isPrimaryTopicOf Eledoisin.