Matches in DBpedia 2014 for { <http://dbpedia.org/resource/Entacapone> ?p ?o. }
- Entacapone abstract "Entacapone (INN) (/ˌɛntəkəˈpoʊn/ or /ɛnˈtækəpoʊn/) is a drug that functions as a catechol-O-methyl transferase (COMT) inhibitor. It is used in the treatment of Parkinson's disease. When administered in conjunction with dopaminergic agents such as L-DOPA, entacapone prevents COMT from metabolizing L-DOPA into 3-methoxy-4-hydroxy-L-phenylalanine (3-OMD) in the periphery, which does not easily cross the blood brain barrier (BBB). Pharmacologically, entacapone is somewhat similar to carbidopa or benserazide, in that it is an inhibitor of an enzyme that converts L-DOPA into a compound that cannot cross the blood brain barrier. Carbidopa and benserazide inhibit aromatic L-amino acid decarboxylase, which converts L-DOPA into dopamine, which cannot cross the blood brain barrier. Entacapone is a member of the class of drugs known as nitrocatechols.".
- Entacapone atcPrefix "N04".
- Entacapone atcSuffix "BX02".
- Entacapone bioavailability "35.0".
- Entacapone casNumber "130929-57-6".
- Entacapone chEBI "4798".
- Entacapone drugbank "DB00494".
- Entacapone fdaUniiCode "4975G9NM6T".
- Entacapone iupacName "(2E)-2-cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N,N-diethylprop-2-enamide".
- Entacapone pubchem "5281081".
- Entacapone thumbnail Entacapone2DACS.svg?width=300.
- Entacapone wikiPageExternalLink www.comtan.com.
- Entacapone wikiPageExternalLink ucm206513.htm.
- Entacapone wikiPageExternalLink a601236.html.
- Entacapone wikiPageExternalLink www.stalevo.com.
- Entacapone wikiPageID "3208946".
- Entacapone wikiPageRevisionID "580326948".
- Entacapone atcPrefix "N04".
- Entacapone atcSuffix "BX02".
- Entacapone bioavailability "35.0".
- Entacapone c "14".
- Entacapone casNumber "130929".
- Entacapone chebi "4798".
- Entacapone chembl "953".
- Entacapone chemspiderid "4444537".
- Entacapone dailymedid "e41bbc90-bb83-4514-a38f-994e9fa76472".
- Entacapone drugbank "DB00494".
- Entacapone eliminationHalfLife "-2520.0".
- Entacapone excretion "Faeces , Urine".
- Entacapone h "15".
- Entacapone hasPhotoCollection Entacapone.
- Entacapone image "Entacapone3Dan.gif".
- Entacapone inchi "1".
- Entacapone inchikey "JRURYQJSLYLRLN-BJMVGYQFBD".
- Entacapone iupacName "-2".
- Entacapone kegg "D00781".
- Entacapone legalAu "S4".
- Entacapone legalCa "Rx-only".
- Entacapone legalUk "POM".
- Entacapone legalUs "Rx-only".
- Entacapone medlineplus "a601236".
- Entacapone metabolism Liver.
- Entacapone molecularWeight "305.286".
- Entacapone n "3".
- Entacapone o "5".
- Entacapone pregnancyAu "B3".
- Entacapone pregnancyUs "C".
- Entacapone proteinBound "98.0".
- Entacapone pubchem "5281081".
- Entacapone routesOfAdministration "Oral".
- Entacapone smiles "[O-][N+]c1ccccc1O".
- Entacapone stdinchi "1".
- Entacapone stdinchikey "JRURYQJSLYLRLN-BJMVGYQFSA-N".
- Entacapone tradename "Comtan , Stalevo".
- Entacapone unii "4975".
- Entacapone verifiedrevid "477167001".
- Entacapone width "200".
- Entacapone subject Category:Amides.
- Entacapone subject Category:COMT_inhibitors.
- Entacapone subject Category:Catechols.
- Entacapone subject Category:Nitriles.
- Entacapone subject Category:Nitrobenzenes.
- Entacapone type Abstraction100002137.
- Entacapone type Amide114724264.
- Entacapone type Amides.
- Entacapone type Chemical114806838.
- Entacapone type Compound114818238.
- Entacapone type Material114580897.
- Entacapone type Matter100020827.
- Entacapone type Nitrile114827346.
- Entacapone type Nitriles.
- Entacapone type Nitrobenzene114963486.
- Entacapone type Nitrobenzenes.
- Entacapone type OrganicCompound114727670.
- Entacapone type Part113809207.
- Entacapone type PhysicalEntity100001930.
- Entacapone type Relation100031921.
- Entacapone type Substance100019613.
- Entacapone type Drug.
- Entacapone type DrugProduct.
- Entacapone type FunctionalSubstance.
- Entacapone comment "Entacapone (INN) (/ˌɛntəkəˈpoʊn/ or /ɛnˈtækəpoʊn/) is a drug that functions as a catechol-O-methyl transferase (COMT) inhibitor. It is used in the treatment of Parkinson's disease. When administered in conjunction with dopaminergic agents such as L-DOPA, entacapone prevents COMT from metabolizing L-DOPA into 3-methoxy-4-hydroxy-L-phenylalanine (3-OMD) in the periphery, which does not easily cross the blood brain barrier (BBB).".
- Entacapone label "Entacapon".
- Entacapone label "Entacapone".
- Entacapone label "Entacapone".
- Entacapone label "Entacapone".
- Entacapone label "Entacapone".
- Entacapone label "Entacapone".
- Entacapone label "Entakapon".
- Entacapone label "エンタカポン".
- Entacapone label "恩他卡朋".
- Entacapone sameAs Entacapon.
- Entacapone sameAs Entacapone.
- Entacapone sameAs Entacapone.
- Entacapone sameAs エンタカポン.
- Entacapone sameAs Entacapone.
- Entacapone sameAs Entakapon.
- Entacapone sameAs Entacapone.
- Entacapone sameAs m.08zfpy.
- Entacapone sameAs Q416444.