Matches in DBpedia 2014 for { <http://dbpedia.org/resource/Ezetimibe> ?p ?o. }
- Ezetimibe abstract "Ezetimibe /ɛˈzɛtɨmɪb/ is a drug that lowers plasma cholesterol levels. It acts by decreasing cholesterol absorption in the small intestine. It may be used alone (marketed as Zetia or Ezetrol), when other cholesterol-lowering medications are not tolerated, or together with statins (e.g., ezetimibe/simvastatin, marketed as Vytorin and Inegy) when statins alone do not control cholesterol. However, none of the studies have shown that ezetimibe reduced heart attack, stroke or death. Panels and experts have said that ezetimibe should only be used as a last resort for patients who can't tolerate other drugs, and possibly not even then. They have complained that ezetimibe is overpromoted and overprescribed. In the ARBITER 6-HALTS trial, subjects taking a statin plus ezetimibe had an increase in carotid intima–media thickness (CIMT), which is a measurement of the thickness of the arteries and correlated with atherosclerotic disease. They also had more adverse cardiovascular events than subjects taking a statin plus niacin. Subjects in the statin/niacin group had a decrease in CIMT thickness. Britain's NICE statement, published in 2007, endorses its use for monotherapy if statins are not tolerated or as add-on therapy.".
- Ezetimibe atcPrefix "C10".
- Ezetimibe atcSuffix "AX09".
- Ezetimibe bioavailability "35.0".
- Ezetimibe casNumber "163222-33-1".
- Ezetimibe chEBI "49040".
- Ezetimibe drugbank "DB00973".
- Ezetimibe fdaUniiCode "EOR26LQQ24".
- Ezetimibe iupacName "(3R,4S)-1-(4-fluorophenyl)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)azetidin-2-one".
- Ezetimibe pubchem "150311".
- Ezetimibe thumbnail Ezetimibe.svg?width=300.
- Ezetimibe wikiPageExternalLink dpdirect.jsp?name=Ezetimibe.
- Ezetimibe wikiPageExternalLink www.zetia.com.
- Ezetimibe wikiPageExternalLink index.jsp.
- Ezetimibe wikiPageID "864202".
- Ezetimibe wikiPageRevisionID "605315468".
- Ezetimibe atcPrefix "10.0".
- Ezetimibe atcSuffix "AX09".
- Ezetimibe bioavailability "35".
- Ezetimibe c "24".
- Ezetimibe casNumber "163222".
- Ezetimibe chebi "49040".
- Ezetimibe chembl "1138".
- Ezetimibe chemspiderid "132493".
- Ezetimibe drugbank "DB00973".
- Ezetimibe eliminationHalfLife "108000.0".
- Ezetimibe excretion "Renal 11%, faecal 78%".
- Ezetimibe f "2".
- Ezetimibe h "21".
- Ezetimibe hasPhotoCollection Ezetimibe.
- Ezetimibe inchi "1".
- Ezetimibe inchikey "OLNTVTPDXPETLC-XPWALMASBY".
- Ezetimibe iupacName "-1".
- Ezetimibe kegg "D01966".
- Ezetimibe legalAu "S4".
- Ezetimibe legalCa "Rx-only".
- Ezetimibe legalUk "POM".
- Ezetimibe legalUs "Rx-only".
- Ezetimibe medlineplus "a603015".
- Ezetimibe meltingHigh "166".
- Ezetimibe meltingPoint "164".
- Ezetimibe metabolism "Intestinal wall, hepatic".
- Ezetimibe molecularWeight "409.4".
- Ezetimibe n "1".
- Ezetimibe o "3".
- Ezetimibe pregnancyAu "C".
- Ezetimibe pregnancyUs "C".
- Ezetimibe proteinBound ">90%".
- Ezetimibe pubchem "150311".
- Ezetimibe routesOfAdministration "Oral".
- Ezetimibe smiles "Fc1ccc[C@@H]CC[C@H]4CN[C@@H]4c3ccccc3".
- Ezetimibe stdinchi "1".
- Ezetimibe stdinchikey "OLNTVTPDXPETLC-XPWALMASSA-N".
- Ezetimibe tradename "Zetia".
- Ezetimibe unii "EOR26LQQ24".
- Ezetimibe verifiedrevid "461098524".
- Ezetimibe watchedfields "changed".
- Ezetimibe width "200".
- Ezetimibe subject Category:Azetidines.
- Ezetimibe subject Category:Hypolipidemic_agents.
- Ezetimibe subject Category:Lactams.
- Ezetimibe subject Category:Merck.
- Ezetimibe subject Category:Organofluorides.
- Ezetimibe subject Category:Phenols.
- Ezetimibe subject Category:Schering-Plough.
- Ezetimibe type Abstraction100002137.
- Ezetimibe type Chemical114806838.
- Ezetimibe type Compound114818238.
- Ezetimibe type Material114580897.
- Ezetimibe type Matter100020827.
- Ezetimibe type OrganicCompound114727670.
- Ezetimibe type Part113809207.
- Ezetimibe type Phenol114989545.
- Ezetimibe type Phenols.
- Ezetimibe type PhysicalEntity100001930.
- Ezetimibe type Relation100031921.
- Ezetimibe type Substance100019613.
- Ezetimibe type Drug.
- Ezetimibe type DrugProduct.
- Ezetimibe type FunctionalSubstance.
- Ezetimibe comment "Ezetimibe /ɛˈzɛtɨmɪb/ is a drug that lowers plasma cholesterol levels. It acts by decreasing cholesterol absorption in the small intestine. It may be used alone (marketed as Zetia or Ezetrol), when other cholesterol-lowering medications are not tolerated, or together with statins (e.g., ezetimibe/simvastatin, marketed as Vytorin and Inegy) when statins alone do not control cholesterol. However, none of the studies have shown that ezetimibe reduced heart attack, stroke or death.".
- Ezetimibe label "Ezetimib".
- Ezetimibe label "Ezetimiba".
- Ezetimibe label "Ezetimiba".
- Ezetimibe label "Ezetimibe".
- Ezetimibe label "Ezetimibe".
- Ezetimibe label "Ezetymib".
- Ezetimibe label "Ézétimibe".
- Ezetimibe label "Эзетимиб".
- Ezetimibe label "إزيتمايب".
- Ezetimibe sameAs Ezetimib.
- Ezetimibe sameAs Ezetimiba.
- Ezetimibe sameAs Ézétimibe.
- Ezetimibe sameAs Ezetimibe.
- Ezetimibe sameAs Ezetymib.
- Ezetimibe sameAs Ezetimiba.
- Ezetimibe sameAs m.03jkvr.
- Ezetimibe sameAs Q417997.
- Ezetimibe sameAs Q417997.
- Ezetimibe sameAs ezetimibe.