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- simvastatin abstract "Ezetimibe/simvastatin /ɛˈzɛtɨmɪb ˌsɪmvəˈstætɨn/ is a drug combination used for the treatment of dyslipidemia. It is a combination of ezetimibe (known as Zetia in the United States and Ezetrol elsewhere) and the statin drug simvastatin (known as Zocor in the U.S.). The combination preparation is marketed by Merck & Co. under the trade names Vytorin and Inegy.Ezetimibe reduces blood cholesterol by acting at the brush border of the small intestine and inhibiting the absorption of cholesterol, leading to a decrease in the delivery of intestinal cholesterol to the liver.Simvastatin is an HMG-CoA reductase inhibitor or statin. It works by blocking an enzyme that is necessary for the body to make cholesterol.Even though ezetimibe decreases cholesterol levels, as of 2009 it has not been found to lead to improvement in real world outcomes. The combination of simvastatin and ezetimibe has not been found to be any better than simvastatin alone. A panel of experts thus concluded in 2008 that it should "only be used as a last resort".".
- simvastatin atcPrefix "C10".
- simvastatin atcSuffix "BA02".
- simvastatin casNumber "444313-53-5".
- simvastatin thumbnail Ezetimibe.png?width=300.
- simvastatin wikiPageExternalLink simvastatin.
- simvastatin wikiPageExternalLink Vytorintab.htm.
- simvastatin wikiPageExternalLink www.vytorin.com.
- simvastatin wikiPageID "1004541".
- simvastatin wikiPageRevisionID "591271380".
- simvastatin atcPrefix "10.0".
- simvastatin atcSuffix "BA02".
- simvastatin casNumber "444313".
- simvastatin chemspiderid "21106308".
- simvastatin class "Statin HMG-CoA reductase inhibitor".
- simvastatin class "via Niemann-Pick C1-Like 1 protein".
- simvastatin component "Ezetimibe".
- simvastatin component "Simvastatin".
- simvastatin hasPhotoCollection simvastatin.
- simvastatin image "Simvastatin.svg".
- simvastatin inchi "1".
- simvastatin inchikey "PNAMDJVUJCJOIX-UYWVIEDUBS".
- simvastatin legalStatus "Rx".
- simvastatin routesOfAdministration "Oral".
- simvastatin smiles "Fc1ccc[C@H]CC[C@@H]4[C@@H]NC4=O.CCCO[C@H]2C[C@@H]\C=C3\C=C/[C@H][C@H][C@@H]23".
- simvastatin stdinchi "1".
- simvastatin stdinchikey "PNAMDJVUJCJOIX-UYWVIEDUSA-N".
- simvastatin type "combo".
- simvastatin verifiedrevid "448787104".
- simvastatin width "180".
- simvastatin width "200".
- simvastatin subject Category:Combination_drugs.
- simvastatin subject Category:Hypolipidemic_agents.
- simvastatin subject Category:Merck.
- simvastatin subject Category:Schering-Plough.
- simvastatin type Agent109190918.
- simvastatin type Agent114778436.
- simvastatin type CausalAgent100007347.
- simvastatin type CombinationDrugs.
- simvastatin type Drug103247620.
- simvastatin type HypolipidemicAgents.
- simvastatin type Matter100020827.
- simvastatin type PhysicalEntity100001930.
- simvastatin type Substance100020090.
- simvastatin type Drug.
- simvastatin type DrugProduct.
- simvastatin type FunctionalSubstance.
- simvastatin comment "Ezetimibe/simvastatin /ɛˈzɛtɨmɪb ˌsɪmvəˈstætɨn/ is a drug combination used for the treatment of dyslipidemia. It is a combination of ezetimibe (known as Zetia in the United States and Ezetrol elsewhere) and the statin drug simvastatin (known as Zocor in the U.S.). The combination preparation is marketed by Merck & Co.".
- simvastatin label "Ezetimibe/simvastatin".
- simvastatin sameAs m.03ygmc.
- simvastatin sameAs Q5423256.
- simvastatin sameAs Q5423256.
- simvastatin sameAs DB00973.
- simvastatin sameAs simvastatin.
- simvastatin wasDerivedFrom simvastatin?oldid=591271380.
- simvastatin depiction Ezetimibe.png.
- simvastatin homepage www.vytorin.com.
- simvastatin isPrimaryTopicOf simvastatin.