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- FKBP1A abstract "Peptidyl-prolyl cis-trans isomerase FKBP1A is an enzyme that in humans is encoded by the FKBP1A gene.The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 (tacrolimus) and rapamycin (sirolimus). It interacts with several intracellular signal transduction proteins including type I TGF-beta receptor. It also interacts with multiple intracellular calcium release channels including the tetrameric skeletal muscle ryanodine receptor. In mouse, deletion of this homologous gene causes congenital heart disorder known as noncompaction of left ventricular myocardium. There is evidence of multiple alternatively spliced transcript variants for this gene, but the full length nature of some variants has not been determined.".
- FKBP1A entrezgene "2280".
- FKBP1A wikiPageID "14125710".
- FKBP1A wikiPageRevisionID "603878851".
- FKBP1A hasPhotoCollection FKBP1A.
- FKBP1A requireManualInspection "no".
- FKBP1A summaryText "The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin . It interacts with several intracellular signal transduction proteins including type I TGF-beta receptor. It also interacts with multiple intracellular calcium release channels including the tetrameric skeletal muscle ryanodine receptor. In mouse, deletion of this homologous gene causes congenital heart disorder known as noncompaction of left ventricular myocardium. There is evidence of multiple alternatively spliced transcript variants for this gene, but the full length nature of some variants has not been determined.".
- FKBP1A updateCitations "yes".
- FKBP1A updatePage "yes".
- FKBP1A updateProteinBox "yes".
- FKBP1A updateSummary "yes".
- FKBP1A type Biomolecule.
- FKBP1A type Protein.
- FKBP1A type BiologicalObject.
- FKBP1A comment "Peptidyl-prolyl cis-trans isomerase FKBP1A is an enzyme that in humans is encoded by the FKBP1A gene.The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 (tacrolimus) and rapamycin (sirolimus).".
- FKBP1A label "FKBP1A".
- FKBP1A label "FKBP1A".
- FKBP1A sameAs FKBP1A.
- FKBP1A sameAs m.03cvcz6.
- FKBP1A sameAs Q5426014.
- FKBP1A sameAs Q5426014.
- FKBP1A sameAs 2238.
- FKBP1A sameAs 3484.
- FKBP1A sameAs 768.
- FKBP1A wasDerivedFrom FKBP1A?oldid=603878851.
- FKBP1A isPrimaryTopicOf FKBP1A.