Matches in DBpedia 2014 for { <http://dbpedia.org/resource/Fentanyl> ?p ?o. }
- Fentanyl abstract "Fentanyl (also known as fentanil, brand names Sublimaze, Actiq, Durogesic, Duragesic, Fentora, Matrifen, Haldid, Onsolis, Instanyl, Abstral, Lazanda and others) is a potent, synthetic opioid analgesic with a rapid onset and short duration of action. It is a strong agonist at the μ-opioid receptors. Historically it has been used to treat breakthrough pain and is commonly used in pre-procedures as a pain reliever as well as an anesthetic in combination with a benzodiazepine.Fentanyl is approximately 50-100 times more potent than morphine on a dose-by-dose basis.Fentanyl was first synthesized by Paul Janssen in 1960 following the medical inception of pethidine several years earlier. Janssen developed fentanyl by assaying analogues of the structurally related drug pethidine for opioid activity. The widespread use of fentanyl triggered the production of fentanyl citrate (the salt formed by combining fentanyl and citric acid in a 1:1 stoichiometry), which entered the clinical practice as a general anaesthetic under the trade name Sublimaze in the 1960s. Following this, many other fentanyl analogues were developed and introduced into medical practice, including sufentanil, alfentanil, remifentanil, and lofentanil.In the mid-1990s, fentanyl was first introduced for widespread palliative use with the clinical introduction of the Duragesic patch, followed in the next decade by the introduction of the first quick-acting prescription formations of fentanyl for personal use, the Actiq lollipop and Fentora buccal tablets. Through the delivery method of transdermal patches, as of 2012 fentanyl was the most widely used synthetic opioid in clinical practice,[citation needed] with several new delivery methods now available, including a sublingual spray for cancer patients.Fentanyl and its derivatives are used recreationally. Deaths have resulted from both recreational and medical use, some because of malfunctioning patches.".
- Fentanyl atcPrefix "N01".
- Fentanyl atcSuffix "AH01".
- Fentanyl bioavailability "33.0".
- Fentanyl bioavailability "50.0".
- Fentanyl bioavailability "89.0".
- Fentanyl bioavailability "92.0".
- Fentanyl casNumber "437-38-7".
- Fentanyl chEBI "119915".
- Fentanyl drugbank "DB00813".
- Fentanyl fdaUniiCode "UF599785JZ".
- Fentanyl iupacName "N-(1-(2-phenylethyl)-4-piperidinyl)-N-phenylpropanamide".
- Fentanyl pubchem "3345".
- Fentanyl thumbnail Fentanyl2DACS.svg?width=300.
- Fentanyl wikiPageExternalLink dpdirect.jsp?name=Fentanyl.
- Fentanyl wikiPageExternalLink 2377563.stm.
- Fentanyl wikiPageExternalLink EmergencyResponseCard_29750022.html.
- Fentanyl wikiPageExternalLink news_reader.aspx?ID=1041238.
- Fentanyl wikiPageExternalLink a605043.html.
- Fentanyl wikiPageExternalLink fentanyl.htm.
- Fentanyl wikiPageExternalLink fentanyl.html.
- Fentanyl wikiPageID "141915".
- Fentanyl wikiPageRevisionID "603918492".
- Fentanyl atcPrefix "N01".
- Fentanyl atcSuffix "AH01".
- Fentanyl bioavailability "33.0".
- Fentanyl bioavailability "50.0".
- Fentanyl bioavailability "89.0".
- Fentanyl bioavailability "92.0".
- Fentanyl c "22".
- Fentanyl casNumber "437".
- Fentanyl chebi "119915".
- Fentanyl chembl "596".
- Fentanyl chemspiderid "3228".
- Fentanyl dependencyLiability "Moderate – high".
- Fentanyl drugbank "DB00813".
- Fentanyl eliminationHalfLife "-1200.0".
- Fentanyl eliminationHalfLife "-14400.0".
- Fentanyl eliminationHalfLife "390.0".
- Fentanyl eliminationHalfLife "97200.0".
- Fentanyl excretion "60".
- Fentanyl h "28".
- Fentanyl hasPhotoCollection Fentanyl.
- Fentanyl image "Fentanyl3Dan2.gif".
- Fentanyl inchi "1".
- Fentanyl iupacName "N--N-phenylpropanamide".
- Fentanyl iupharLigand "1626".
- Fentanyl kegg "D00320".
- Fentanyl legalAu "S8".
- Fentanyl legalUk "Class A".
- Fentanyl legalUs "Schedule II".
- Fentanyl meltingPoint "87.5".
- Fentanyl metabolism "hepatic, primarily by CYP3A4".
- Fentanyl molecularWeight "336.471".
- Fentanyl n "2".
- Fentanyl o "1".
- Fentanyl pregnancyAu "C".
- Fentanyl pregnancyUs "C".
- Fentanyl proteinBound "80".
- Fentanyl pubchem "3345".
- Fentanyl routesOfAdministration Intramuscular_injection.
- Fentanyl routesOfAdministration Intravenous_therapy.
- Fentanyl routesOfAdministration Oral_mucosa.
- Fentanyl routesOfAdministration Route_of_administration.
- Fentanyl routesOfAdministration Sublingual_administration.
- Fentanyl routesOfAdministration Transdermal_patch.
- Fentanyl smiles "O=CNC3=CC=CC=C3".
- Fentanyl stdinchi "1".
- Fentanyl stdinchikey "PJMPHNIQZUBGLI-UHFFFAOYSA-N".
- Fentanyl tradename "Actiq, Duragesic, Fentora, Sublimaze and others".
- Fentanyl unii "UF599785JZ".
- Fentanyl verifiedrevid "443760208".
- Fentanyl watchedfields "changed".
- Fentanyl width "200".
- Fentanyl subject Category:Addictive_drugs.
- Fentanyl subject Category:Anilides.
- Fentanyl subject Category:Belgian_inventions.
- Fentanyl subject Category:Euphoriants.
- Fentanyl subject Category:General_anesthetics.
- Fentanyl subject Category:Janssen_Pharmaceutica.
- Fentanyl subject Category:Mu-opioid_agonists.
- Fentanyl subject Category:Piperidines.
- Fentanyl subject Category:Propionamides.
- Fentanyl subject Category:Synthetic_opioids.
- Fentanyl type Agent114778436.
- Fentanyl type Anesthetic102710766.
- Fentanyl type CausalAgent100007347.
- Fentanyl type Drug103247620.
- Fentanyl type GeneralAnesthetic103433434.
- Fentanyl type GeneralAnesthetics.
- Fentanyl type Matter100020827.
- Fentanyl type PhysicalEntity100001930.
- Fentanyl type Substance100020090.
- Fentanyl type Drug.
- Fentanyl type DrugProduct.
- Fentanyl type FunctionalSubstance.
- Fentanyl comment "Fentanyl (also known as fentanil, brand names Sublimaze, Actiq, Durogesic, Duragesic, Fentora, Matrifen, Haldid, Onsolis, Instanyl, Abstral, Lazanda and others) is a potent, synthetic opioid analgesic with a rapid onset and short duration of action. It is a strong agonist at the μ-opioid receptors.".
- Fentanyl label "Fentanil".
- Fentanyl label "Fentanilo".
- Fentanyl label "Fentanyl".