Matches in DBpedia 2014 for { <http://dbpedia.org/resource/Fibrinogen> ?p ?o. }
- Fibrinogen abstract "Fibrinogen (factor I) is a soluble, 340 kDa plasma glycoprotein, that is converted by thrombin into fibrin during blood clot formation. Fibrinogen is synthesized in the liver by the hepatocytes. The concentration of fibrinogen in the blood plasma is 200–400 mg/dL (normally measured using the Clauss method).During normal blood coagulation, a coagulation cascade activates the zymogen prothrombin by converting it into the serine protease thrombin. Thrombin then converts the soluble fibrinogen into insoluble fibrin strands. These strands are then cross-linked by factor XIII to form a blood clot. FXIIIa stabilizes fibrin further by incorporation of the fibrinolysis inhibitors alpha-2-antiplasmin and TAFI (thrombin activatable fibrinolysis inhibitor, procarboxypeptidase B), and binding to several adhesive proteins of various cells. Both the activation of Factor XIII by thrombin and plasminogen activator (t-PA) are catalyzed by fibrin. Fibrin specifically binds the activated coagulation factors factor Xa and thrombin and entraps them in the network of fibers, thus functioning as a temporary inhibitor of these enzymes, which stay active and can be released during fibrinolysis. Recent research has shown that fibrin plays a key role in the inflammatory response and development of rheumatoid arthritis.[citation needed]".
- Fibrinogen arm "q".
- Fibrinogen band "28".
- Fibrinogen chromosome "4".
- Fibrinogen entrezgene "2243".
- Fibrinogen entrezgene "2244".
- Fibrinogen entrezgene "2266".
- Fibrinogen hgncid "3661".
- Fibrinogen hgncid "3662".
- Fibrinogen hgncid "3694".
- Fibrinogen omim "134820".
- Fibrinogen omim "134830".
- Fibrinogen omim "134850".
- Fibrinogen refseq "NM_000508".
- Fibrinogen refseq "NM_005141".
- Fibrinogen refseq "NM_021870".
- Fibrinogen symbol "FGA".
- Fibrinogen symbol "FGB".
- Fibrinogen symbol "FGG".
- Fibrinogen symbol "Fib_alpha".
- Fibrinogen symbol "Fibrinogen_C".
- Fibrinogen symbol "Fibrinogen_aC".
- Fibrinogen thumbnail Fibrinandligand.png?width=300.
- Fibrinogen uniprot "P02671".
- Fibrinogen uniprot "P02675".
- Fibrinogen uniprot "P02679".
- Fibrinogen wikiPageExternalLink Page1.htm.
- Fibrinogen wikiPageExternalLink link?SOURCE=Reactome&ID=REACT_214.
- Fibrinogen wikiPageID "238687".
- Fibrinogen wikiPageRevisionID "604709938".
- Fibrinogen arm "q".
- Fibrinogen band "28".
- Fibrinogen caption "Crystallographic structure of a fragment of human fibrin.".
- Fibrinogen caption "crystal structure of native chicken fibrinogen with two different bound ligands".
- Fibrinogen caption "nmr solution structure, stability, and interaction of the recombinant bovine fibrinogen alphac-domain fragment".
- Fibrinogen chromosome "4".
- Fibrinogen entrezgene "2243".
- Fibrinogen entrezgene "2244".
- Fibrinogen entrezgene "2266".
- Fibrinogen hasPhotoCollection Fibrinogen.
- Fibrinogen hgncid "3661".
- Fibrinogen hgncid "3662".
- Fibrinogen hgncid "3694".
- Fibrinogen interpro "IPR002181".
- Fibrinogen interpro "IPR012290".
- Fibrinogen interpro "IPR021996".
- Fibrinogen name FGG.
- Fibrinogen name Fibrinogen_alpha_chain.
- Fibrinogen name Fibrinogen_beta_chain.
- Fibrinogen name "Fibrinogen alpha C domain".
- Fibrinogen name "Fibrinogen alpha/beta chain family".
- Fibrinogen name "Fibrinogen beta and gamma chains, C-terminal globular domain".
- Fibrinogen omim "134820".
- Fibrinogen omim "134830".
- Fibrinogen omim "134850".
- Fibrinogen pfam "PF00147".
- Fibrinogen pfam "PF08702".
- Fibrinogen pfam "PF12160".
- Fibrinogen pfamClan "CL0422".
- Fibrinogen prosite "PDOC00445".
- Fibrinogen refseq "NM_000508".
- Fibrinogen refseq "NM_005141".
- Fibrinogen refseq "NM_021870".
- Fibrinogen scop "1".
- Fibrinogen symbol FGG.
- Fibrinogen symbol Fibrinogen_alpha_chain.
- Fibrinogen symbol Fibrinogen_beta_chain.
- Fibrinogen symbol "Fib_alpha".
- Fibrinogen symbol "Fibrinogen_C".
- Fibrinogen symbol "Fibrinogen_aC".
- Fibrinogen uniprot "P02671".
- Fibrinogen uniprot "P02675".
- Fibrinogen uniprot "P02679".
- Fibrinogen subject Category:Acute_phase_proteins.
- Fibrinogen subject Category:Blood_proteins.
- Fibrinogen subject Category:Coagulation_system.
- Fibrinogen type Biomolecule.
- Fibrinogen type Protein.
- Fibrinogen type BiologicalObject.
- Fibrinogen comment "Fibrinogen (factor I) is a soluble, 340 kDa plasma glycoprotein, that is converted by thrombin into fibrin during blood clot formation. Fibrinogen is synthesized in the liver by the hepatocytes. The concentration of fibrinogen in the blood plasma is 200–400 mg/dL (normally measured using the Clauss method).During normal blood coagulation, a coagulation cascade activates the zymogen prothrombin by converting it into the serine protease thrombin.".
- Fibrinogen label "Fibrinogeen".
- Fibrinogen label "Fibrinogen".
- Fibrinogen label "Fibrinogen".
- Fibrinogen label "Fibrinogeno".
- Fibrinogen label "Fibrinogène".
- Fibrinogen label "Fibrinogênio".
- Fibrinogen label "Fibrinógeno".
- Fibrinogen label "Fibrynogen".
- Fibrinogen label "Фибриноген".
- Fibrinogen label "فيبرينوجين".
- Fibrinogen label "纖維蛋白原".
- Fibrinogen sameAs Fibrinogen.
- Fibrinogen sameAs Fibrinogen.
- Fibrinogen sameAs Fibrinógeno.
- Fibrinogen sameAs Fibrinogeno.
- Fibrinogen sameAs Fibrinogène.
- Fibrinogen sameAs Fibrinogen.
- Fibrinogen sameAs Fibrinogeno.
- Fibrinogen sameAs Fibrinogeen.
- Fibrinogen sameAs Fibrynogen.