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- Frank_Bassen abstract "Frank Albert Bassen (1903–2003) practiced as a haematologist and internist in New York, 1933–1978, in affiliation with Mount Sinai Hospital. He was born 14 November 1903 in St. George, New Brunswick, Canada and graduated from McGill University. He emigrated to the United States via Vanceboro, Maine, in 1928 and was subsequently naturalized as a citizen of the United States. He died in 2003 at the age of 99 years.In partnership with Abraham Kornzweig, Bassen identified Bassen-Kornzweig disease, a rare autosomal recessive disorder in which the body fails to produce chylomicrons, a low density lipoprotein (LDL) and very low density lipoprotein (VLDL). Individuals with this condition are unable to properly digest fats. Symptoms include ataxia, peripheral neuropathy and other forms of nerve dysfunction. Treatment includes vitamin E.Characteristics of the syndrome include the presence of acanthocytes (burr-cell malformation of the erythrocytes), and the reduction or even absence of B-lipoproteins. Complications include retinitis pigmentosa, degenerative changes in the central nervous system involving the cerebellum and long tracts, fatty diarrhea, ataxia, areflexia, demyelination, defective intestinal lipid absorption with low serum cholesterol level, intestinal malabsorption, amaurosis, retarded growth, and steatorrhea. Intellectual development may be slightly retarded.Many afflicted with the syndrome are unable to walk.The syndrome appears in infancy. Affected children appear normal at birth but usually fail to thrive during their first year. The syndrome may predominate in males (71%). Most cases occur in children of Jewish descent, especially among Ashkenazi Jews. The disease is transmitted as an autosomal recessive trait. It is also commonly recognized as a betalipoprotein deficiency or abetalipoproteinemia.".
- Frank_Bassen birthDate "1903".
- Frank_Bassen birthYear "1903".
- Frank_Bassen deathDate "2003".
- Frank_Bassen deathYear "2003".
- Frank_Bassen wikiPageID "27122319".
- Frank_Bassen wikiPageRevisionID "604199499".
- Frank_Bassen dateOfBirth "1903".
- Frank_Bassen dateOfDeath "2003".
- Frank_Bassen hasPhotoCollection Frank_Bassen.
- Frank_Bassen name "Bassen, Frank Albert Md".
- Frank_Bassen shortDescription "American physician".
- Frank_Bassen description "American physician".
- Frank_Bassen description "American physician".
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- Frank_Bassen comment "Frank Albert Bassen (1903–2003) practiced as a haematologist and internist in New York, 1933–1978, in affiliation with Mount Sinai Hospital. He was born 14 November 1903 in St. George, New Brunswick, Canada and graduated from McGill University. He emigrated to the United States via Vanceboro, Maine, in 1928 and was subsequently naturalized as a citizen of the United States.".
- Frank_Bassen label "Frank Bassen".
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- Frank_Bassen givenName "Frank Albert Md".
- Frank_Bassen isPrimaryTopicOf Frank_Bassen.
- Frank_Bassen name "Bassen, Frank Albert Md".
- Frank_Bassen name "Frank Albert Md Bassen".
- Frank_Bassen surname "Bassen".