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- Free_androgen_index abstract "Free Androgen Index or FAI is a ratio used to determine abnormal androgen status in humans. The ratio is the total testosterone level divided by the sex hormone binding globulin (SHBG) level, and then multiplying by a constant, usually 100. The concentrations of testosterone and SHBG are normally measured in nanomols per liter. FAI has no units.The majority of testosterone in the blood does not exist as the free molecule. Instead around half is tightly bound to sex hormone binding globulin, and the other half is weakly bound to albumin. Only a small percentage is unbound, under 3% in females, and less than 0.7% in males. Since only the free testosterone is able to bind to tissue receptors to exert its effects, it is believed that free testosterone is the best marker of a person's androgen status. However, free testosterone is difficult and expensive to measure, and many laboratories do not offer this service.The free androgen index is intended to give a guide to the free testosterone level, but it is not very accurate. Consequently, there are no universally agreed 'normal ranges', and levels slightly above or below quoted laboratory reference ranges may not be clinically significant.Reference ranges depend on the constant in the calculation - 100 is used in the formula above, and the following suggested ranges are based on this. As with any laboratory measurement, however, it is vital that results are compared against the reference range quoted for that laboratory. Neither FAI nor free or total testosterone measurements should be interpreted in isolation; as a bare minimum, gonadotropin levels should also be measured.[citation needed]As a guide, in healthy adult men typical FAI values are 30-150. Values below 30 may indicate testosterone deficiency, which may contribute to fatigue, erectile dysfunction, osteoporosis and loss of secondary sex characteristics.[citation needed] In women, androgens are most often measured when there is concern that they may be raised (as in hirsutism or the polycystic ovary syndrome). Typical values for the FAI in women are 7-10.[citation needed]".
- Free_androgen_index wikiPageExternalLink zb158-a.pdf.
- Free_androgen_index wikiPageExternalLink 471.
- Free_androgen_index wikiPageID "12096154".
- Free_androgen_index wikiPageRevisionID "596341191".
- Free_androgen_index hasPhotoCollection Free_androgen_index.
- Free_androgen_index subject Category:Androgens.
- Free_androgen_index subject Category:Testosterone.
- Free_androgen_index type Abstraction100002137.
- Free_androgen_index type Androgen114747587.
- Free_androgen_index type Androgens.
- Free_androgen_index type BodySubstance105263850.
- Free_androgen_index type Hormone105407119.
- Free_androgen_index type LiquidBodySubstance105397468.
- Free_androgen_index type Matter100020827.
- Free_androgen_index type Part113809207.
- Free_androgen_index type PhysicalEntity100001930.
- Free_androgen_index type Relation100031921.
- Free_androgen_index type Secretion105404728.
- Free_androgen_index type SteroidHormone114745635.
- Free_androgen_index type Substance100019613.
- Free_androgen_index comment "Free Androgen Index or FAI is a ratio used to determine abnormal androgen status in humans. The ratio is the total testosterone level divided by the sex hormone binding globulin (SHBG) level, and then multiplying by a constant, usually 100. The concentrations of testosterone and SHBG are normally measured in nanomols per liter. FAI has no units.The majority of testosterone in the blood does not exist as the free molecule.".
- Free_androgen_index label "Free androgen index".
- Free_androgen_index label "Freier Androgenindex".
- Free_androgen_index sameAs Freier_Androgenindex.
- Free_androgen_index sameAs m.02vpq8_.
- Free_androgen_index sameAs Q5500183.
- Free_androgen_index sameAs Q5500183.
- Free_androgen_index sameAs Free_androgen_index.
- Free_androgen_index wasDerivedFrom Free_androgen_index?oldid=596341191.
- Free_androgen_index isPrimaryTopicOf Free_androgen_index.