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- Free_base abstract "Freebase or free base refers to the pure basic form of an amine, as opposed to its salt form. The amine is usually an alkaloid natural product. Free base is commonly used in organic chemistry and pharmaceuticals to describe the deprotonated amine form of a compound.Most alkaloids are unstable in their pure form and exist in ionic salt form. The salts usually exhibit greater water solubility. Common counterions include chloride, bromide, acetate and oxalate. Because of the ubiquity of chloride salts, formed from the reaction of the amine with hydrochloric acid, these amine derivatives are known as the hydrochlorides. For example, compare the free base hydroxylamine (NH2OH) with hydroxylamine hydrochloride (NH3OH+ Cl-).The term "freebasing" means converting an ionic form into free base. It can refer to deprotonating the hydrochloride salt form of cocaine to free base form. The process provides for some merits of acid-base extraction. The free base is preferred for smoking because the evaporation point of the free base is further apart from the burning point compared to the hydrochloride salt, making the salt form more prone to destruction by pyrolysis. Some of the active drug is lost in the deprotonation process. Freebasing can also refer to the consumption by smoking of free base cocaine (crack cocaine) or heroin. Freebasing became popular in the United States during the 1980s, mainly because of the fear of diseases such as HIV and viral hepatitis, since users did not have to share hypodermic needles.".
- Free_base wikiPageID "12730565".
- Free_base wikiPageRevisionID "575523406".
- Free_base hasPhotoCollection Free_base.
- Free_base subject Category:Alkaloids.
- Free_base subject Category:Bases.
- Free_base subject Category:Drug_culture.
- Free_base type Abstraction100002137.
- Free_base type Alkaloid114712692.
- Free_base type Alkaloids.
- Free_base type Bases.
- Free_base type Chemical114806838.
- Free_base type Compound114818238.
- Free_base type Footing113790912.
- Free_base type Foundation113790712.
- Free_base type Material114580897.
- Free_base type Matter100020827.
- Free_base type OrganicCompound114727670.
- Free_base type Part113809207.
- Free_base type PhysicalEntity100001930.
- Free_base type Relation100031921.
- Free_base type Substance100019613.
- Free_base comment "Freebase or free base refers to the pure basic form of an amine, as opposed to its salt form. The amine is usually an alkaloid natural product. Free base is commonly used in organic chemistry and pharmaceuticals to describe the deprotonated amine form of a compound.Most alkaloids are unstable in their pure form and exist in ionic salt form. The salts usually exhibit greater water solubility. Common counterions include chloride, bromide, acetate and oxalate.".
- Free_base label "Free base".
- Free_base label "Free base".
- Free_base sameAs Free_base.
- Free_base sameAs m.0d6fx.
- Free_base sameAs Q280190.
- Free_base sameAs Q280190.
- Free_base sameAs Free_base.
- Free_base wasDerivedFrom Free_base?oldid=575523406.
- Free_base isPrimaryTopicOf Free_base.