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- Fumarase abstract "Fumarase (or fumarate hydratase) is an enzyme that catalyzes the reversible hydration/dehydration of fumarate to malate. Fumarase comes in two forms: mitochondrial and cytosolic. The mitochondrial isoenzyme is involved in the Krebs Cycle (also known as the Tricarboxylic Acid Cycle [TCA] or the Citric Acid Cycle), and the cytosolic isoenzyme is involved in the metabolism of amino acids and fumarate. Subcellular localization is established by the presence of a signal sequence on the amino terminus in the mitochondrial form, while subcellular localization in the cytosolic form is established by the absence of the signal sequence found in the mitochondrial variety.This enzyme participates in 3 metabolic pathways: citric acid cycle, reductive citric acid cycle (CO2 fixation), and in renal cell carcinoma. Mutations in this gene have been associated with the development of leiomyomas in the skin and uterus in combination with renal cell carcinoma.".
- Fumarase ecNumber "4.2.1.2".
- Fumarase thumbnail FumaraseDimer.png?width=300.
- Fumarase wikiPageExternalLink L-malate.html.
- Fumarase wikiPageExternalLink fumarate.html.
- Fumarase wikiPageExternalLink Fumarate%20Hydratase%20(final).doc.
- Fumarase wikiPageExternalLink krebs.html.
- Fumarase wikiPageID "4032737".
- Fumarase wikiPageRevisionID "594271262".
- Fumarase arm "q".
- Fumarase band "42.1".
- Fumarase caption "Fumarase active site".
- Fumarase caption "Structure of yeast fumarase.".
- Fumarase casNumber "9032".
- Fumarase chromosome "1".
- Fumarase ecNumber "4.2".
- Fumarase ecnumber "4.2".
- Fumarase entrezgene "2271".
- Fumarase goCode "4333".
- Fumarase hasPhotoCollection Fumarase.
- Fumarase hgncid "3700".
- Fumarase interpro "IPR004646".
- Fumarase iubmbEcNumber "4".
- Fumarase name "Fumarate hydratase".
- Fumarase name "fumarate hydratase".
- Fumarase omim "136850".
- Fumarase pdb ", , , , , , , , , ,".
- Fumarase pfam "PF05681".
- Fumarase refseq "NM_000143".
- Fumarase symbol "FH".
- Fumarase symbol "Fumarase".
- Fumarase uniprot "P07954".
- Fumarase subject Category:EC_4.2.1.
- Fumarase type Biomolecule.
- Fumarase type Enzyme.
- Fumarase type ProteinMolecule.
- Fumarase type BiologicalObject.
- Fumarase comment "Fumarase (or fumarate hydratase) is an enzyme that catalyzes the reversible hydration/dehydration of fumarate to malate. Fumarase comes in two forms: mitochondrial and cytosolic. The mitochondrial isoenzyme is involved in the Krebs Cycle (also known as the Tricarboxylic Acid Cycle [TCA] or the Citric Acid Cycle), and the cytosolic isoenzyme is involved in the metabolism of amino acids and fumarate.".
- Fumarase label "Fumarasa".
- Fumarase label "Fumarase".
- Fumarase label "Fumarase".
- Fumarase label "Fumarase".
- Fumarase label "Fumarase".
- Fumarase label "Fumarato idratasi".
- Fumarase label "延胡索酸酶".
- Fumarase sameAs Fumaráza.
- Fumarase sameAs Fumarase.
- Fumarase sameAs Fumarasa.
- Fumarase sameAs Fumarase.
- Fumarase sameAs Fumarato_idratasi.
- Fumarase sameAs Fumarase.
- Fumarase sameAs m.0bdj87.
- Fumarase sameAs Q418634.
- Fumarase sameAs Q418634.
- Fumarase wasDerivedFrom Fumarase?oldid=594271262.
- Fumarase depiction FumaraseDimer.png.
- Fumarase isPrimaryTopicOf Fumarase.
- Fumarase name "fumarate hydratase".