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- Futile_cycle abstract "A futile cycle, also known as a substrate cycle, occurs when two metabolic pathways run simultaneously in opposite directions and have no overall effect other than to dissipate energy in the form of heat. For example, if glycolysis and gluconeogenesis were to be active at the same time, glucose would be converted to pyruvate by glycolysis and then converted back to glucose by gluconeogenesis, with an overall consumption of ATP. Futile cycles may have a role in metabolic regulation, where a futile cycle would be a system oscillating between two states and very sensitive to small changes in the activity of any of the enzymes involved. The cycle does generate heat, and may be used to maintain thermal homeostasis, for example in the brown adipose tissue of young mammals, or to generate heat rapidly, for example in insect flight muscles and in hibernating animals during periodical arousal from torpor.It has been reported that the glucose metabolism substrate cycle is not a futile cycle but a regulatory process. For example, when energy is suddenly needed, ATP is replaced by AMP, a much more reactive adenine.".
- Futile_cycle thumbnail Biochem_reaction_arrow_forward_NNNN_horiz_med.png?width=300.
- Futile_cycle wikiPageID "10059553".
- Futile_cycle wikiPageRevisionID "605217848".
- Futile_cycle hasPhotoCollection Futile_cycle.
- Futile_cycle subject Category:Glycolysis.
- Futile_cycle subject Category:Metabolism.
- Futile_cycle comment "A futile cycle, also known as a substrate cycle, occurs when two metabolic pathways run simultaneously in opposite directions and have no overall effect other than to dissipate energy in the form of heat. For example, if glycolysis and gluconeogenesis were to be active at the same time, glucose would be converted to pyruvate by glycolysis and then converted back to glucose by gluconeogenesis, with an overall consumption of ATP.".
- Futile_cycle label "Futile cycle".
- Futile_cycle label "Substratzyklus".
- Futile_cycle label "無益回路".
- Futile_cycle sameAs Substratzyklus.
- Futile_cycle sameAs 無益回路.
- Futile_cycle sameAs m.02q0hcb.
- Futile_cycle sameAs Q905391.
- Futile_cycle sameAs Q905391.
- Futile_cycle wasDerivedFrom Futile_cycle?oldid=605217848.
- Futile_cycle depiction Biochem_reaction_arrow_forward_NNNN_horiz_med.png.
- Futile_cycle isPrimaryTopicOf Futile_cycle.