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- GSTM2 abstract "Glutathione S-transferase Mu 2 is an enzyme that in humans is encoded by the GSTM2 gene.Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs.".
- GSTM2 entrezgene "2946".
- GSTM2 wikiPageID "14773531".
- GSTM2 wikiPageRevisionID "591522313".
- GSTM2 hasPhotoCollection GSTM2.
- GSTM2 requireManualInspection "no".
- GSTM2 summaryText "Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs.".
- GSTM2 updateCitations "yes".
- GSTM2 updatePage "yes".
- GSTM2 updateProteinBox "yes".
- GSTM2 updateSummary "yes".
- GSTM2 type Biomolecule.
- GSTM2 type Protein.
- GSTM2 type BiologicalObject.
- GSTM2 comment "Glutathione S-transferase Mu 2 is an enzyme that in humans is encoded by the GSTM2 gene.Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class.".
- GSTM2 label "GSTM2".
- GSTM2 sameAs m.03gxjsl.
- GSTM2 sameAs Q5514628.
- GSTM2 sameAs Q5514628.
- GSTM2 sameAs 2165.
- GSTM2 sameAs 3110.
- GSTM2 sameAs 3304.
- GSTM2 wasDerivedFrom GSTM2?oldid=591522313.
- GSTM2 isPrimaryTopicOf GSTM2.