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- Ganirelix abstract "Ganirelix acetate (or diacetate) is an injectable competitive gonadotropin-releasing hormone antagonist (GnRH antagonist). It is primarily used in assisted reproduction to control ovulation. The drug works by blocking the action of GnRH upon the pituitary, thus rapidly suppressing the production and action of LH and FSH. Ganirelix is used in fertility treatment to prevent premature ovulation that could result in the harvesting of eggs that are too immature to be used in procedures such as in vitro fertilisation.GnRH agonists are also sometimes used in reproductive therapy, as well as to treat disorders involving sex-steroid hormones, such as endometriosis. One advantage of using GnRH antagonists is that repeated administration of GnRH agonists results in decreased levels of gonadotropins and sex steroids due to desensitization of the pituitary. This is avoided when using GnRH antagonists such as Ganirelix. The success of Ganirelix in reproductive therapy has been shown to be comparable to that when using GnRH agonists.Ganirelix is derived from GnRH itself, with amino acid substitutions made at positions 1, 2, 3, 6, 8, and 10.The European Commission gave marketing authorization for Ganirelix throughout the European Union to N.V. Organon in May 2000. Ganirelix is marketed by Organon International as Antagon.".
- Ganirelix atcPrefix "H01".
- Ganirelix atcSuffix "CC01".
- Ganirelix bioavailability "91.1".
- Ganirelix casNumber "129311-55-3".
- Ganirelix fdaUniiCode "IX503L9WN0".
- Ganirelix iupacName "(2S)-1-[(2S)-2-[[(2S)-2-[[(2R)-2-[[(2R)-2-[[(2S)-2-[[(2R)-2-[[(2R)-2-[[(2R)-2-acetamido-3-naphthalen-2-ylpropanoyl]amino]-3-(4-chlorophenyl)propanoyl]amino]-3-pyridin-3-ylpropanoyl]amino]-3-hydroxypropanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-6-[bis(ethylamino)methylideneamino]hexanoyl]amino]-4-methylpentanoyl]amino]-6-[bis(ethylamino)methylideneamino]hexanoyl]-N-[(2R)-1-amino-1-oxopropan-2-yl]pyrrolidine-2-carboxamide".
- Ganirelix pubchem "16186319".
- Ganirelix thumbnail Ganirelix.svg?width=300.
- Ganirelix wikiPageID "9526638".
- Ganirelix wikiPageRevisionID "587387840".
- Ganirelix atcPrefix "H01".
- Ganirelix atcSuffix "CC01".
- Ganirelix bioavailability "91.1".
- Ganirelix c "80".
- Ganirelix casNumber "129311".
- Ganirelix chembl "1251".
- Ganirelix chemspiderid "16736620".
- Ganirelix cl "1".
- Ganirelix eliminationHalfLife "58320.0".
- Ganirelix excretion Feces.
- Ganirelix excretion Kidney.
- Ganirelix h "113".
- Ganirelix hasPhotoCollection Ganirelix.
- Ganirelix iupacName "-1".
- Ganirelix kegg "D08010".
- Ganirelix legalUs "Rx-only".
- Ganirelix molecularWeight "1570.4".
- Ganirelix n "18".
- Ganirelix o "13".
- Ganirelix pregnancyUs "X".
- Ganirelix proteinBound "81.9".
- Ganirelix pubchem "16186319".
- Ganirelix routesOfAdministration Subcutaneous_injection.
- Ganirelix stdinchi "1".
- Ganirelix stdinchikey "BJQRBVMMHKUPPY-YYXZGPOZSA-N".
- Ganirelix unii "IX503L9WN0".
- Ganirelix verifiedfields "changed".
- Ganirelix verifiedrevid "461118874".
- Ganirelix subject Category:Fertility_medicine.
- Ganirelix subject Category:GnRH_antagonists.
- Ganirelix type Adversary109773245.
- Ganirelix type CausalAgent100007347.
- Ganirelix type GnRHAntagonists.
- Ganirelix type LivingThing100004258.
- Ganirelix type Object100002684.
- Ganirelix type Organism100004475.
- Ganirelix type Person100007846.
- Ganirelix type PhysicalEntity100001930.
- Ganirelix type Whole100003553.
- Ganirelix type YagoLegalActor.
- Ganirelix type YagoLegalActorGeo.
- Ganirelix type Drug.
- Ganirelix type DrugProduct.
- Ganirelix type FunctionalSubstance.
- Ganirelix comment "Ganirelix acetate (or diacetate) is an injectable competitive gonadotropin-releasing hormone antagonist (GnRH antagonist). It is primarily used in assisted reproduction to control ovulation. The drug works by blocking the action of GnRH upon the pituitary, thus rapidly suppressing the production and action of LH and FSH.".
- Ganirelix label "Ganirelix".
- Ganirelix label "Ganirelix".
- Ganirelix sameAs Ganirelix.
- Ganirelix sameAs m.02phwnx.
- Ganirelix sameAs Q5521314.
- Ganirelix sameAs Q5521314.
- Ganirelix sameAs ganirelix.
- Ganirelix sameAs Ganirelix.
- Ganirelix wasDerivedFrom Ganirelix?oldid=587387840.
- Ganirelix depiction Ganirelix.svg.
- Ganirelix isPrimaryTopicOf Ganirelix.